72072-16-3 Usage
Uses
Used in Pharmaceutical Industry:
4-Butyl-2-methylaniline is used as a chemical intermediate for the preparation of a number of substituted acetamides. These acetamides are antagonists of MDR (multidrug resistance) proteins, which play a crucial role in the treatment of drug-resistant cancers. By inhibiting the action of MDR proteins, these substituted acetamides can enhance the effectiveness of chemotherapeutic drugs and overcome resistance in cancer cells, thereby improving the therapeutic outcomes for patients with drug-resistant cancers.
Check Digit Verification of cas no
The CAS Registry Mumber 72072-16-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,7 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 72072-16:
(7*7)+(6*2)+(5*0)+(4*7)+(3*2)+(2*1)+(1*6)=103
103 % 10 = 3
So 72072-16-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H17N/c1-3-4-5-10-6-7-11(12)9(2)8-10/h6-8H,3-5,12H2,1-2H3
72072-16-3Relevant academic research and scientific papers
MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
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Paragraph 00826, (2017/08/01)
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
