72078-90-1Relevant academic research and scientific papers
A convenient method for synthesizing modified 4-nitrophenols
Nakaike, Yumi,Kamijo, Yoshio,Mori, Satoshi,Tamura, Mina,Nishiwaki, Nagatoshi,Ariga, Masahiro
, p. 10169 - 10171 (2007/10/03)
β-Nitroenamine having a formyl group behaves as the synthetic equivalent of unstable nitromalonaldehyde upon treatment with ketones under basic conditions and leads to 2,6-disubstituted 4-nitrophenols. The present method is safer than the conventional one using sodium nitromalonaldehyde and enables the preparation of hitherto unknown nitrophenols.
Nucleophilic Reaction upon Electron-deficient Pyridone Derivatives. IV. Ring Transformation of 1-Substituted 3,5-Dinitro-2-pyridones with Ketones in the Presence of Amines
Matsumura, Eizo,Tohda, Yasuo,Ariga, Masahiro
, p. 2174 - 2180 (2007/10/02)
Ring transformation of 1-substituted 3,5-dinitro-2-pyridones with 1,3-disubstituted acetones in the presence of secondary or primary amines gave p-nitroaniline derivatives and N-substituted 2-nitroacetamide.Two types of enamine intermediates, 2-azabicyclononene derivatives and N-substituted 2-(5-amino-2-nitro-2,4-cyclohexadienyl)-2-nitroacetamides were isolated and characterized.The course of the base-catalyzed reaction is interpreted.
