72100-53-9Relevant academic research and scientific papers
Heterocondensed thiophenes and thiazoles by Thorpe-Ziegler cyclization
Gruner, Margit,Boettcher, Gesine,Gewald, Karl
, p. 1071 - 1076 (2008/12/20)
(Chemical Equation Presented) The syntheses of novel thieno-pyridones, thiazolo-pyridones, thiazolo-pyridines and amino- and diamino-dieno-pyridines were described. Simultaneously, it was demonstrated that in these compounds and in the related 3-aminothio
Traceless solid-phase synthesis of 2,4,5-trisubstituted thiazoles
Lee, Ill Young,Lee, Jin Young,Lee, Hye Jin,Gong, Young-Dae
, p. 2483 - 2485 (2007/10/03)
The solid-phase synthesis of trisubstituted thiazoles is described. The synthetic strategy involves the formation of a polymer-bound thiazole by reacting resin-bound cyanodithioimidocarbonic acid and α-bromoketone. The resin-bound thiazole was reacted with acyl chlorides or isocyanates. After oxidation-activation of a thioether linker to a sulfone linker, traceless cleavage was achieved with nucleophiles to give trisubstituted thiazoles. Georg Thieme Verlag Stuttgart.
Heterocyclic Cation Systems. 14. Synthesis of Thienodiazepine, Thiazolodiazepine, and s-Triazolothiazolodiazepine Derivatives
Hirai, Kentaro,Sugimoto, Hirohiko,Ishiba, Teruyuki
, p. 253 - 260 (2007/10/02)
Synthesis of heterodiazepines is described.The synthetic route involved reactions of the anion of malononitrile or cyanamide toward 2-substituted 1,3-oxathiolium cation 1 to give amino ketone derivatives 3 and 4 as the key intermediates.Introducti
