72104-28-0Relevant academic research and scientific papers
A water-soluble “turn-on” fluorescent probe for specifically imaging mitochondria viscosity in living cells
Wang, Hui,Fang, Bin,Xiao, Lufei,Li, Di,Zhou, Le,Kong, Lin,Yu, Yan,Li, Xiangzi,Wu, Yunjun,Hu, Zhangjun
, p. 127 - 131 (2018)
Rational design of water-soluble probes for mitochondrial viscosity in practical biological applications remains a challenge. Herein, we described a novel hydro soluble benzothiazole salt derivative MitoSN, which exhibits specifically response and singular sensitivity to the mitochondria viscosity in living Hela cells. MitoSN displays an excellent fluorescence enhancement (ca. 35-fold) with the increase of the viscosity in the water-glycerol system. Moreover, confocal microscopy indicates that MitoSN is sensitive to the local viscosity and selectively stains mitochondria, the body of zebrafish as well. Importantly, MitoSN is capable to identify the viscosity difference of mitochondria in normal and nystatin treated Hela cells. The work provides a useful tool to monitor the changes of viscosity in the mitochondrial microenvironment.
Syntheses and spectroscopic properties of energy transfer systems based on squaraines
Jiao, Guan-Sheng,Loudet, Aurore,Lee, Hong Boon,Kalinin, Stanislav,Johansson, Lennart B.-?.,Burgess, Kevin
, p. 3109 - 3116 (2003)
The purpose of this project was to prepare fluorescent dyes that could absorb energy at relatively short wavelengths, and fluoresce in the near-IR region. To achieve this, copper- and palladium-mediated C-N couplings were used to prepare the 'cassettes', i.e the carbazole derivative 3b and the carbazole-, phenothiazine-, and phenoazine-squaraines 4b-d. These compounds have carbazole, phenothiazine, and phenoazine donor-components that absorb around about 300-320nm, and squaraine acceptor-parts that fluoresce in the range 650-700nm. The efficiencies of energy transfer from the donor to the acceptor, and the overall quantum yields of the cassettes were determined.
2-Methylthiazolium Salts as 1,4-Dinucleophiles. Thiazolopyridinium Salts from Westphal Condensation
Galera, C.,Vaquero, J. J.,Navio, Garcia J. L.,Alvarez-Builla, J.
, p. 1889 - 1892 (2007/10/02)
Condensation of 2-methylthiazolium salts with 1,2-dicarbonyls in the presence of base, yielded thiazolopyridinium derivatives.Results with different substrates are discussed.
