72139-48-1Relevant academic research and scientific papers
Synthesis of 2-amino-5-pyrimidinecarbonitrile derivatives
Cocco,Congiu,Onnis,Maccioni
, p. 529 - 530 (2007/10/02)
2-Amino-4-dialkylamino- or -4-ethoxy-6-methylthio-5-pyrimidine-carbonitriles 3 are obtained through a base-induced reaction between 3-amino-3-(dialkylamino)propenenitriles 1 and N-[bis(methylthio)methylene]cyanamide (2).
Synthesis of 6-Amino and 6-Ethoxy-2(1H)-pyridone Derivatives
Cocco, Maria Teresa,Congiu, Cenzo,Maccioni, Antonio,Plumitallo, Antonio
, p. 1859 - 1862 (2007/10/02)
An efficient route allowing the synthesis of 6-amino and 6-ethoxy-2-(1H)pyridone derivatives by reaction of ethyl cyanoacetimidate, ethyl ethoxycarbonylacetimidate and related acetamidines with diethyl ethoxymethylenemalonate (EMME) is reported.The formation of dienamino derivatives as intermediates and their heterocyclization to the 2(1H)-pyridone derivatives is described.
3-Chlor-5-dimethylamino-2-formyl-4-aza-2,4-pentadiennitril, Synthese und Umsetzungen mit Nucleophilen
Klemm, Kurt,Pruesse, Wolfgang,Baron, Lothar,Daltrozzo, Ewald
, p. 2001 - 2018 (2007/10/02)
3-Chloro-5-dimethylamino-2-formyl-4-aza-2,4-pentadienenitrile (7) is prepared by partial hydrolysis of the iminium perchlorate 1.In 7 the electrophilic centres (1, 3, 5) regioselectively react with secondary alkylamines, arylamines, and hydrazine derivatives to yield 3-amino-substituted formylazapentadienenitriles and (hydrazonomethyl)azapentadienenitriles.Intramolecular cyclisation leads to triazole betaines, pyrazoles, and 1,4-dihydropyrimidines.
