721448-99-3

Upstream product

• 721448-92-6 7-benzyloxy-3,3-bis-(tert-butyl-dimethyl-silanyloxymethyl)-3H-isobenzofuran-1-one 
• 721448-75-5 3,3-bis-(tert-butyl-dimethyl-silanyloxymethyl)-7-hydroxy-3H-isobenzofuran-1-one 
• 721448-94-8 acetic acid 4-benzyloxy-1-hydroxymethyl-3-oxo-1,3-dihydro-isobenzofuran-1-ylmethyl ester 
• 721448-93-7 7-benzyloxy-3,3-bis-hydroxymethyl-3H-isobenzofuran-1-one 
• 721448-74-4 2-{[tert-butyl(dimethyl)silyl]oxy}-N,N-diethylbenzamide 
• 100-39-0 benzyl bromide 
• 19311-91-2 N,N-diethylsalicylamide 
• 721448-97-1 acetic acid 4-benzyloxy-1-(tert-butyl-dimethyl-silanyloxymethyl)-3-oxo-1,3-dihydro-isobenzofuran-1-ylmethyl ester 

Relevant academic research and scientific papers

Design, synthesis, and structure-activity relationship of new isobenzofuranone ligands of protein kinase C

Protein kinase C (PKC) is a family of enzymes, which play important roles in intracellular signal transduction. We have designed novel PKC ligands having an isobenzofuranone template, based on the proposed interaction of DAG (1,2-diacyl-sn-glycerol) with