72150-22-2

Basic information

• Product Name: 4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one
• Synonyms: 4,10-dioxatricyclo[5.2.1.0(2,6)]decan-8-en-3-one;4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one;3a,4,7,7a-tetrahydro-4,7-epoxyisobenzofuran-1(3H)-one;4,10-Dioxatricyclo[5.2.1.02,6]decan-8-en-3-one
• CAS NO: 72150-22-2
• Molecular Formula: C₈H₈O₃
• Molecular Weight: 152.15
• Mol File: 72150-22-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 93 °C
• Boiling Point: 338 °C at 760 mmHg
• Flash Point: 139.8 °C
• Appearance: /
• Density: 1.366 g/cm³
• Vapor Pressure: 0.000101mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: 4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one(72150-22-2)
• EPA Substance Registry System: 4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one(72150-22-2)

Safety Data

• Hazardous Substances Data: 72150-22-2(Hazardous Substances Data)

Usage

General Description

4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one is a chemical compound with a complex molecular structure. It is a cyclic organic compound with a tetrahydroisobenzofuran ring and an epoxy group attached to it. 4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one is a lactone, which is a type of cyclic ester. It is often used as an intermediate in the synthesis of various pharmaceuticals and other organic compounds. It may also have potential applications in the field of organic chemistry and chemical synthesis. Due to its unique structure, 4,7-epoxy-3a,4,7,7a-tetrahydroisobenzofuran-1(3h)-one may have interesting reactivity and properties, making it a valuable target for further research and exploration in the field of organic chemistry.

InChI:InChI=1/C8H8O3/c9-8-7-4(3-10-8)5-1-2-6(7)11-5/h1-2,4-7H,3H2

Upstream product

• 51112-81-3 endo, cis-7-oxabicyclo<2.2.1>hept-5-ene-2,3-dicarboxylic acid 
• 6766-44-5 7-oxabicyclo<2.2.1>heptene-exo-2,3-dicarboxylic anhydride 
• 6118-51-0 exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 

Downstream Products

• 135440-55-0 6-exo-(3,5-dinitrobenzoyloxymethyl)-5-exo-vinyl-7-oxabicyclo<2.2.1>hept-2-ene 
• 135440-53-8 2-(Diphenyl-phosphinoyl)-1-((1R,2R,3S,4S)-3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)-ethanol 
• 119119-26-5 tert-Butyl-diphenyl-(1-{(E)-2-[(1R,2S,3S,4S)-3-(tetrahydro-pyran-2-yloxymethyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-vinyl}-hexyloxy)-silane 
• 119119-16-3 tert-Butyl-diphenyl-{(1R,2R,3R,4S)-3-[(E)-3-(tetrahydro-pyran-2-yloxy)-propenyl]-7-oxa-bicyclo[2.2.1]hept-5-en-2-ylmethoxy}-silane 
• 135440-52-7 5-exo-(2'-diphenylphosphinoyl-1'-oxoethyl)-6-exo-hydroxymethyl-7-oxabicyclo<2.2.1>hept-2-ene hemiacetal 
• 109685-75-8 (1S,2S,6S,7R,8S,9S)-8-Chloro-9-phenylsulfanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-74-7 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-phenylsulfanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-77-0 (1R,2R,6R,7S,8R,9R)-8-Chloro-9-(2-nitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-76-9 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-(2-nitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 6253-21-0 3α-hydroxymethyl-7α-oxabicyclo[2.2.1]heptane-2α-carboxylic acid lactone 
• 109685-79-2 (1S,2S,6S,7R,8S,9S)-8-Chloro-9-(2,4-dinitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-78-1 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-(2,4-dinitro-phenylsulfanyl)-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-81-6 (1S,2S,6S,7R,8S,9S)-8-Chloro-9-phenylselanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 
• 109685-80-5 (1R,2R,6R,7S,8S,9S)-9-Chloro-8-phenylselanyl-4,10-dioxa-tricyclo[5.2.1.0^2,6]decan-3-one 

Relevant articles and documents

A new approach to the synthesis of 1,3-aminoalcohols from meso cyclic acid anhydride

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Synthesis and in vitro pharmacology of 7-oxabicyclo[2.2.1]heptane analogues of thromboxane A2/PGH2

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Synthesis of thromboxane A2 analogue (+/-)-(9,11),(11,12)-dideoxa-(9,11a)-oxa thromboxane A2

A synthesis of the thromboxane A2 analogue, (+/-)-(9,11),(11,12)-dideoxa-(9,11a)-oxa-thromboxane A2 (TXA2) starting from the exo-adduct 3 of maleic anhydride and furan is described