72159-38-7

Upstream product

• 917-64-6 methyl magnesium iodide 
• 33985-40-9 (3aR,4S,6R,6aR)-tetrahydro-6-methoxy-2,2-dimethylfuro-[3,4-d][1,3]dioxole-4-carbaldehyde 
• 122-04-3 4-nitro-benzoyl chloride 
• 53270-44-3 methyl 2,3-O-isopropylidene-6-deoxy-β-D-allofuranoside 
• 28538-26-3 methyl 6-deoxy-2,3-O-isopropylidene-alpha-L-talo-furanoside 
• 62-23-7 4-nitro-benzoic acid 

Downstream Products

• 80851-27-0 methyl 6-deoxy-2,3,5-tri-O-(p-nitrobenzoyl)-beta-D-allofuranoside 
• 80851-28-1 6-deoxy-2,3,5-tri-O-(p-nitrobenzoyl)-beta-D-allofuranosyl bromide 
• 72159-39-8 methyl 6-deoxy-5-o-(p-nitrobenzoyl)-beta-D-allofuranoside 

Relevant academic research and scientific papers

Synthesis of 5'-C-methyl-D-allo- and L-talo-ribonucleoside 3'-O- phosphoramidites and their incorporation into hammerhead ribozymes

5'-C-Methyl-D-allo and L-talo-ribonucleoside 3'-O-phosphoramidites were prepared from L-rhamnose in 13 and 15 steps respectively. Incorporation of L-talo residues in the hammerhead ribozyme and the resulting activity and stability of the modified ribozyme

SYNTHESIS OF CRYSTALLINE DERIVATIVES OF 6-DEOXY-D-ALLO- AND -L-TALO-FURANOSYL BROMIDE SUITABLE FOR NUCLEOSIDE SYNTHESIS

6-Deoxy-2,3,5-tri-O-(p-nitrobenzoyl)-beta-D-allo- and -alpha-L-talo-furanosyl bromide (6 and 11) have been synthesized from methyl 2,3-O-isopropylidene-beta-D-ribo-pentodialdo-1,4-furanoside (1).Treatment of 1 with methyl Grignard reagent, followed by (p-