7218-21-5

Basic information

• Product Name: 2,4-Cyclohexadien-1-one, 6-(acetyloxy)-2,6-dimethyl-
• CAS NO: 7218-21-5
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol File: 7218-21-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,4-Cyclohexadien-1-one, 6-(acetyloxy)-2,6-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Cyclohexadien-1-one, 6-(acetyloxy)-2,6-dimethyl-(7218-21-5)
• EPA Substance Registry System: 2,4-Cyclohexadien-1-one, 6-(acetyloxy)-2,6-dimethyl-(7218-21-5)

Safety Data

• Hazardous Substances Data: 7218-21-5(Hazardous Substances Data)

Upstream product

• 576-26-1 2.6-dimethylphenol 
• 108-24-7 acetic anhydride 
• 40430-74-8 Acetic acid (1R,2R,7S,8S,11S)-11-acetoxy-3,5,8,11-tetramethyl-4,12-dioxo-tricyclo[6.2.2.0^2,7]dodeca-5,9-dien-3-yl ester 
• 546-67-8 lead(IV) tetraacetate 

Downstream Products

• 61248-64-4 2-sec-Butoxy-1,3-dimethyl-benzene 
• 90460-53-0 (2RS,3Z,5E)-6-Acetoxy-2-methylhepta-3,5-diensaeure-N-cyclohexylamid 
• 49582-92-5 1,3-diacetoxy-2,4-dimethyl-benzene 
• 20804-41-5 2.4-Dimethyl-3-acetoxy-thiophenol 
• 20804-40-4 3-Hydroxy-2.4-dimethylthiophenol 
• 4674-19-5 3-Carboxymethylmercapto-2,6-dimethyl-1,4-benzochinon 
• 13288-70-5 bis-(3,5-dimethyl-4-hydroxyphenyl)-sulfone 
• 16393-05-8 1,3-Diacetoxy-2,4,5-trimethyl-benzol 
• 6994-64-5 3-amino-2,6-dimethyl-phenol 
• 20951-29-5 2,6-dimethyl-4-(methylsulfonyl)phenol 
• 7379-49-9 2,6-(CH₃)2-4-CH₃S-C₆H₂OH 
• 4962-29-2 4-methoxy-3,5-dimethylphenol 
• 654-42-2 1,4-dihydroxy-2,6-dimethylbenzene 
• 14106-49-1 1-(2,4-Dimethyl-3-hydroxy-phenyl)-semicarbazid 

Relevant articles and documents

Novel one-pot synthesis of acetoxy-2,4-cyclohexadienones

A new, simple, one-pot method for the oxidative acetylation of some substituted phenols leading to acetoxycyclohexa-2,4-dienones is described. A novel diacetoxycyclohexadienone 12 has also been prepared using the present method from 2-hydroxymethyl phenol (salicyl alcohol). Copyright Taylor & Francis, Inc.

?4s+?2s Cycloaddition: Synthesis, Structure and Oxa-di-? Rearrangement of Tricyclo2,6>undecadienones

A simple and efficient synthesis of tricyclo2,6>undecadienones (8-15) is described.The synthesis involves(i) Diels-Alder reaction of a cyclohexadienone (3) and various dienes (4-7) to furnish the keto-acetates (8-11) and (ii) base hydrolysis of 8-11 to the corresponding keto-alcohols (12-15).Photochemical oxa-di-? rearrangement of the cycloadducts (12,13, and 15) to linearly fused polyquinanes (16-18) is also described.The cycloadduct (14) fails to undergo rearrangement possibly due to quenching effect of dienic moiety in the annulated cyclopentene ring.

The stereochemistry and regiochemistry of Diels-Alder reactions of 6-acetoxy-2,6-dimethyl-2,4-cyclohexadienone

6-Acetoxy-2,6-dimethyl-2,4-cyclohexadienone (1) and maleic anhydride in boiling benzene give a single adduct, exo-5-acetoxy-1,5-dimethyl-6-oxobicyclooct-7-ene-endo-2,3-dicarboxylic acid anhydride (2).With propiolic acid 1 gives exo-5-hydroxy-1,5-dimethyl-6-oxobicycloocta-2,7-diene-2-carboxylic acid (15).The high stereoselectivity and regioselectivity of these reactions is interpretable in terms of orbital overlap, closed-shell repulsion, steric, and van der Waals-London effects.