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Phenol, 4-methoxy-3,5-dimethyl-, also known as syringic acid, is a synthetic phenolic compound with the chemical formula C9H12O2. It features a phenol ring with a methoxy group at the 4th carbon position and methyl groups at the 3rd and 5th carbon positions. Phenol, 4-methoxy-3,5-dimethylis known for its unique chemical properties, reactivity, antimicrobial, and antioxidant characteristics.

4962-29-2

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4962-29-2 Usage

Uses

Used in Pharmaceutical Industry:
Phenol, 4-methoxy-3,5-dimethylis utilized as a starting material in the synthesis of various pharmaceuticals due to its unique chemical properties and reactivity. It plays a crucial role in the development of new drugs and medicines.
Used in Chemical Industry:
This phenolic compound is also employed as a starting material in the synthesis of various chemicals, including dyes, due to its reactivity and chemical properties. It contributes to the production of a wide range of chemical products.
Used in Skincare and Personal Care Products:
Phenol, 4-methoxy-3,5-dimethylis used as an ingredient in skincare and personal care products, capitalizing on its antimicrobial and antioxidant properties. It helps to protect the skin from harmful effects of free radicals and supports the development of products with enhanced efficacy and safety.
Used in Antimicrobial Applications:
Due to its antimicrobial properties, Phenol, 4-methoxy-3,5-dimethylis employed in various applications to inhibit the growth of microorganisms, contributing to the preservation and safety of different products.
Used in Antioxidant Formulations:
Leveraging its antioxidant properties, Phenol, 4-methoxy-3,5-dimethylis incorporated into formulations to protect against oxidative stress and support overall health and well-being.

Check Digit Verification of cas no

The CAS Registry Mumber 4962-29-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,6 and 2 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4962-29:
(6*4)+(5*9)+(4*6)+(3*2)+(2*2)+(1*9)=112
112 % 10 = 2
So 4962-29-2 is a valid CAS Registry Number.

4962-29-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methoxy-3,5-dimethylphenol

1.2 Other means of identification

Product number -
Other names Methyl-(4-hydroxy-2.6-dimethyl-phenyl)-aether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4962-29-2 SDS

4962-29-2Relevant academic research and scientific papers

Synthetic method 4 - alkoxyphenol compounds

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Paragraph 0076-0078, (2021/09/29)

The invention discloses a synthetic method of 4 - alkoxyphenol compounds, and belongs to the field of organic chemical synthesis. The method is as follows: An aryl alkyl ether compound is added to the sealing tube. The catalyst dimerization acetic acid rhodium and the oxidizing agent iodobenzene diethyl ester are added, a solvent trifluoroacetic anhydride is added, and the 4 -alkoxyphenol compound is prepared by heating reaction. To the invention, high regioselectivity direct hydroxylation of the aryl alkyl ether compound is realized, the application range of the substrate is wide, the yield is high, the activity after amplification reaction does not significantly decay, and higher yield is still obtained. The utility model has good practicability and industrial application prospect.

Para -Selective hydroxylation of alkyl aryl ethers

Zhu, Runqing,Sun, Qianqian,Li, Jing,Li, Luohao,Gao, Qinghe,Wang, Yakun,Fang, Lizhen

supporting information, p. 13190 - 13193 (2021/12/16)

para-Selective hydroxylation of alkyl aryl ethers is established, which proceeds with a ruthenium(ii) catalyst, hypervalent iodine(iii) and trifluoroacetic anhydride via a radical mechanism. This protocol tolerates a wide scope of substrates and provides a facile and efficient method for preparing clinical drugs monobenzone and pramocaine on a gram scale.

Direct synthesis of anilines and nitrosobenzenes from phenols

St Amant,Frazier,Newmeyer,Fruehauf,Read De Alaniz

supporting information, p. 5520 - 5524 (2016/07/06)

A one-pot synthesis of anilines and nitrosobenzenes from phenols has been developed using an ipso-oxidative aromatic substitution (iSOAr) process. The products are obtained in good yields under mild and metal-free conditions. The leaving group effect on reactions that proceed through mixed quionone monoketals has also been investigated and a predictive model has been established.

Photocatalytic synthesis of dihydrobenzofurans by oxidative [3+2] cycloaddition of phenols

Blum, Travis R.,Zhu, Ye,Nordeen, Sarah A.,Yoon, Tehshik P.

, p. 11056 - 11059 (2015/03/30)

We report a protocol for oxidative [3+2] cycloadditions of phenols and alkenes applicable to the modular synthesis of a large family of dihydrobenzofuran natural products. Visible-light-activated transition metal photocatalysis enables the use of ammonium persulfate as an easily handled benign terminal oxidant. The broad range of organic substrates that are readily oxidized by photoredox catalysis suggests that this strategy may be applicable to a variety of useful oxidative transformations.

Gold-catalyzed dearomative spirocyclization of aryl alkynoate esters

Aparece, Mark D.,Vadola, Paul A.

supporting information, p. 6008 - 6011 (2015/01/08)

Aryl alkynoate esters undergo gold-catalyzed spirocyclization under mild conditions, affording spirolactones in high yields. This approach obviates the need for stoichiometric halogenating reagents typically employed for alkyne activation in related trans

Selective one-pot synthesis of various phenols from diarylethanes

Nakamura, Ryota,Obora, Yasushi,Ishii, Yasutaka

supporting information; experimental part, p. 3417 - 3419 (2009/02/05)

Various substituted phenols were selectively synthesized by a one-pot reaction through the NHPI-catalyzed aerobic oxidation of 1,1-diarylethanes followed by treatment with dilute sulfuric acid. The Royal Society of Chemistry.

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