721888-90-0Relevant academic research and scientific papers
Chemoselective synthesis of aryl carboxamido sulfonic acid derivatives
Yang, Yung-Lin,Rajagopal, Basker,Liang, Chien-Fu,Chen, Chun-Chi,Lai, Hsiu-Ping,Chou, Chih-Hung,Lee, Yen-Pin,Yang, Yen-Ling,Zeng, Jing-Wen,Ou, Chun-Lin,Lin, Po-Chiao
, p. 2640 - 2646 (2013/03/28)
A one-pot two-step synthetic strategy for the preparation of aryl carboxamido sulfonic acid derivatives was developed. The synthesis started from m-(chlorosulfonyl)benzoyl chloride, which was reacted with amines, alcohols, thiols, or sodium azide and cata
THERAPEUTICALLY ACTIVE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER CHARACTERIZED AS HAVING AN IDH MUTATION
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, (2011/06/26)
Compounds and compositions comprising compounds useful in the treatment of cancer are described herein. The compounds and compositions can be used to modulate an isocitrate dehydrogenase (IDH) mutant (e.g., IDHIm or IDH2m) having alpha hydroxyl neoactivity
