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1,8-Naphthyridine-2-acetic acid,5,6,7,8-tetrahydro-,ethyl ester is a heterocyclic chemical compound with potential pharmaceutical applications. It is an ethyl ester derivative of 1,8-Naphthyridine-2-acetic acid, which features a naphthyridine ring. The 5,6,7,8-tetrahydromodification suggests a reduced four-ring structure, which may contribute to its pharmacological properties.
Used in Pharmaceutical Industry:
1,8-Naphthyridine-2-acetic acid,5,6,7,8-tetrahydro-,ethyl ester is used as a potential therapeutic agent for its possible anti-inflammatory, antiviral, or antibacterial effects. Its specific applications are yet to be determined through further research and development, which will help elucidate its full potential in medicine.

721920-80-5

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721920-80-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 721920-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,1,9,2 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 721920-80:
(8*7)+(7*2)+(6*1)+(5*9)+(4*2)+(3*0)+(2*8)+(1*0)=145
145 % 10 = 5
So 721920-80-5 is a valid CAS Registry Number.

721920-80-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)acetate

1.2 Other means of identification

Product number -
Other names 5,6,7,8-tetrahydro-1,8-naphthyridin-2-ylacetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:721920-80-5 SDS

721920-80-5Relevant academic research and scientific papers

ALPHAvBETA1 INTEGRIN ANTAGONISTS

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Paragraph 0173; 0175, (2020/01/31)

The present disclosure provides pharmaceutical agents, including those of the formula: (I) wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods of using the pharmaceutical agents are also provided. The compounds may be used for the inhibition or antagonism of integrins ανβ1 and/or α5β1. In some embodiments, the compounds provided herein exhibit reduced inhibitory or antagonistic activity of integrins ανβ3, ανβ5, ανβ6, ανβ8, and/or αIIbβ3.

INTEGRIN ANTAGONISTS

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Page/Page column 58, (2018/08/03)

The present disclosure provides pharmaceutical agents, including those of the formula:(I) wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Meth

Synthesis of pyrazoles and isoxazoles as potent αvβ3 receptor antagonists

Penning, Thomas D.,Khilevich, Albert,Chen, Barbara B.,Russell, Mark A.,Boys, Mark L.,Wang, Yaping,Duffin, Tiffany,Engleman, V. Wayne,Finn, Mary Beth,Freeman, Sandra K.,Hanneke, Melanie L.,Keene, Jeffery L.,Klover, Jon A.,Nickols, G. Allen,Nickols, Maureen A.,Rader, Randall K.,Settle, Steven L.,Shannon, Kristen E.,Steininger, Christina N.,Westlin, Marisa M.,Westlin, William F.

, p. 3156 - 3161 (2007/10/03)

We describe a series of pyrazole and isoxazole analogs as antagonists of the αvβ3 receptor. Compounds showed low to sub-nanomolar potency against αvβ3, as well as good selectivity against αIIbβ3

PYRAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES

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Page 33, (2010/02/07)

The present invention relates to pharmaceutical compositions comprising compounds of the Formula (I), and methods of selectively inhibiting or antagonizing the αVβ3 and/or the α Vβ5 integrin without significantly inhibitin

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