721923-22-4Relevant academic research and scientific papers
Sodium borohydride/methoxydiethylborane mediated syn-1,3-stereoselective total synthesis of herbarumin-III
Yadav,Narasimhulu,Vikram Reddy,Subba Reddy,Al Khazim Al Ghamdi, Ahmad
experimental part, p. 1075 - 1082 (2011/10/02)
A simple and efficient stereoselective total synthesis of 10-membered macrolide, herbarumin-III is described. The key steps involved in this synthesis are the selective terminal alkylation of ethyl acetoacetate with ethyl bromide, Sharpless epoxidation, NaBH4/Et2BOMe mediated stereoselective syn-1,3-asymmetric reduction, esterification and olefin metathesis.
A concise stereoselective total synthesis of herbarumin III
Yadav, Jhillu S.,Kumar, Veerjala Naveen,Rao, Ramisetti Srinivasa,Srihari, Pabbaraja
experimental part, p. 1938 - 1942 (2009/04/04)
A stereoselective total Synthesis of the phytotoxic compound herbarumin III has been achieved by utilizing Crimmins's aldol approach, 1,3-syn asymmetric reduction, and an olefin metathesis reaction as the key steps.
Formal synthesis of herbarumin III
Gupta, Priti,Kumar, Pradeep
, p. 1688 - 1692 (2008/02/11)
An enantioselective synthesis of herbarumin III is described employing Jacobsen's hydrolytic kinetic resolution and Sharpless asymmetric dihydroxylation as the key steps.
First total synthesis of herbarumin III
Gurjar, Mukund K.,Karmakar, Sukhen,Mohapatra, Debendra K.
, p. 4525 - 4526 (2007/10/03)
An asymmetric 10-step total synthesis of herbarumin III in 24% overall yield is described using ring-closing metathesis as the key step.
