721959-20-2Relevant academic research and scientific papers
Synthesis of analogues of a potent antitumor saponin OSW-1
Morzycki, Jacek W.,Wojtkielewicz, Agnieszka,Wolczynski, Slawomir
, p. 3323 - 3326 (2004)
A series of side chain analogues (5a-e), a 22-glycosylated isomer (10), and 16β-O-L-arabinosyl (13a) or 16β-O-D-xylosyl (13b) analogues of OSW-1 were synthesized. All analogues were found to be less cytotoxic against breast and endometrial cancer cell lines than the natural product.
