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2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 72217-12-0 Structure
  • Basic information

    1. Product Name: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid
    2. Synonyms: 2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-(METHOXYIMINO)ACETIC ACID;(5-AMINO-[1,2,4]THIADIAZOL-3-YL)-METHOXYIMINO-ACETIC ACID;ATDA:( Z ) -2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO ACETIC ACID;2-(5-amino-1,2,4-thiadiazol-3-yl) 2-(Z)-methoxyimino acetic acid;2-METHOXYIMINO-2-(5-ANMINO-1,2,4-THIADIAZOL-3-YL)ACETIC ACID;(Z) -2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic;2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid ,98%;2-(5-Boc-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid
    3. CAS NO:72217-12-0
    4. Molecular Formula: C5H6N4O3S
    5. Molecular Weight: 202.19
    6. EINECS: 1806241-263-5
    7. Product Categories: pharmacetical;Organic acids
    8. Mol File: 72217-12-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 430.4 °C at 760 mmHg
    3. Flash Point: 214.1 °C
    4. Appearance: /
    5. Density: 1.83
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.749
    8. Storage Temp.: 2-8°C(protect from light)
    9. Solubility: N/A
    10. PKA: 2.46±0.41(Predicted)
    11. CAS DataBase Reference: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid(72217-12-0)
    13. EPA Substance Registry System: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid(72217-12-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 72217-12-0(Hazardous Substances Data)

72217-12-0 Usage

Chemical Properties

White solid

Check Digit Verification of cas no

The CAS Registry Mumber 72217-12-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,2,1 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 72217-12:
(7*7)+(6*2)+(5*2)+(4*1)+(3*7)+(2*1)+(1*2)=100
100 % 10 = 0
So 72217-12-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N4O3S/c1-12-8-2(4(10)11)3-7-5(6)13-9-3/h1H3,(H,10,11)(H2,6,7,9)/b8-2-

72217-12-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(5-Amino-1,2,4-Thiadiazol-3-yl)-2-(Methoxyimino)Acetic Acid

1.2 Other means of identification

Product number -
Other names 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72217-12-0 SDS

72217-12-0Relevant articles and documents

Process for preparing 1,2,4-thiadiazole derivatives

-

, (2008/06/13)

An improved process for the production of 5-amino-1,2,4-thiadiazol-3-yl-(2-(lower)-alkoxyimino)acetic acids starting from 5-substituted- or unsubstituted-3-amino-isoxazole compounds is disclosed herein. The title compounds are useful as acylating agents for the production of 7-acylaminocephalosporins.

Practical preparation of (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetic acid: A side-chain of the fourth generation of cephem antibiotics

Tatsuta,Miura,Gunji,Tamai,Yoshida,Inagaki,Kurita

, p. 1701 - 1707 (2007/10/02)

A Z-isomer (4) of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid, which is the common acyl moiety of clinically useful cephem antibiotics, has been prepared from the aminoisoxazoles through the skeletal rearrangement in several routes. Reaction of 3-amino-5-methoxyisoxazole (7) with alkoxycarbonyl isothiocyanates gave methyl 2-(5-alkoxycarbonylamino-1,2,4-thiadiazol-3-yl)acetates (8), which were converted into the target compound 4 through the reaction of the corresponding keto ester with O-methylhydroxylamime. Compound 4 was prepared similarly from 3-aminoisoxazole (10). Also, O-methylation of 2-hydroxyimino-2-(5-methoxycarbonylamino-1,2,4-thiazol-3-yl)acetate (15) with methyl iodide or dimethyl sulfate in the presence of barium oxide and barium hydroxide octahydrate was found to afford exclusively the desired Z-isomer (14a) of methyl 2-(5-methoxycarbonylamino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)aceta te, which was led to 4.

A Practical Preparation of (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic Acid

Tatsuta, Kuniaki,Miura, Shozo,Gunji, Hiroki,Tamai, Tetsuro,Yoshida, Ryonosuke,Inagaki, Takashi

, p. 6423 - 6426 (2007/10/02)

A Z-isomer of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid, which is the common acyl moiety of clinically useful cephalosporins, has been prepared from the aminoisoxazols through the thiadiazol-acetate in two pathways.

Cephalosporin derivatives

-

, (2008/06/13)

7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(substituted)-iminoacetamido]-3-[3-(quaternaryammonio)-1-propen-1-yl]-3-cephem-4-carboxylates of the formula STR1 in which R1 and R2 are defined herein and --≈ N Q is a quaternary ammonio group as defined herein, and salts, solvates, hydrates and esters thereof, are potent antibacterial agents. Processes for their preparation and intermediates in such processes are described.

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