72225-19-5Relevant academic research and scientific papers
Ring-opened analogs of indomethacin affecting human neutrophil functions
Andreani, Aldo,Leoni, Alberto,Locatelli, Alessandra,Morigi, Rita,Rambaldi, Mirella,Gehret, Jean-Claude,Traniello, Serena,Cariani, Alessio,Spisani, Susanna
, p. 299 - 312 (2007/10/03)
A series of ring-opened analogs of indomethacin was synthesized and tested in vitro (at concentrations ranging from 10-9 to 10-5 mol/1) on human neutrophil functions. Two compounds lacking the carboxylic group were subjected to the s
Synthesis of 6,7-dihydrothiazolo[3,2-a]-1,3,5-triazine-4-aryl-2-thiones
Radha Rani,Rahman,Bhalerao
, p. 319 - 325 (2007/10/02)
Reaction of 2-aminothiazoline with aroylisothiocyanate gave 6,7-dihydrothiazolo[3,2-a]-1,3,5-triazine-4-aryl-2-thiones (5) in one step.
2-Aminothiazoline derivatives. Relationships between structure and antiinflammatory activity
Viallet,Boucherle,Cohen-Addad
, p. 553 - 559 (2007/10/05)
Pharmacological studies of 2-aminothiazoline amide and amine derivatives show these compounds to be actively anti-inflammatory. The structure determination by spectroscopic methods and X-ray diffraction indicates a relation between the structure and the activity of these compounds.
