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2-Hydroxyeupatolide, a natural compound derived from the Eupatorium glandulosissimum plant, also known as the Glandular thoroughwort, is a sesquiterpene lactone with notable anti-inflammatory and anti-cancer properties. Its unique chemical structure endows it with the potential to inhibit cancer cell growth and induce apoptosis, while also exhibiting anti-inflammatory and antioxidant effects, positioning it as a promising candidate for future drug development in various medical applications.

72229-33-5

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72229-33-5 Usage

Uses

Used in Cancer Therapy:
2-Hydroxyeupatolide is used as an anti-cancer agent for its ability to inhibit the growth of cancer cells and induce apoptosis in these cells. Its potential use in cancer therapy is supported by its demonstrated effects on various cancer types, making it a valuable asset in the development of novel cancer treatments.
Used in Anti-Inflammatory Applications:
Leveraging its anti-inflammatory properties, 2-Hydroxyeupatolide is used in treating inflammatory conditions. Its capacity to reduce inflammation can be beneficial in managing a range of diseases where inflammation plays a significant role.
Used in Antioxidant Therapy:
2-Hydroxyeupatolide is utilized as an antioxidant agent to combat oxidative stress-related conditions. Its antioxidant effects can protect cells from damage caused by reactive oxygen species, which is particularly important in the context of chronic diseases and aging.
Used in Pharmaceutical Development:
Due to its multifaceted therapeutic potential, 2-Hydroxyeupatolide is used in the development of new pharmaceuticals targeting cancer, inflammation, and oxidative stress. Its unique chemical properties make it a valuable compound for creating innovative drugs and therapies that address these complex health challenges.
Further research is essential to fully explore and understand the potential applications of 2-Hydroxyeupatolide in medicine, ensuring its safe and effective use in treating various conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 72229-33-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,2,2 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 72229-33:
(7*7)+(6*2)+(5*2)+(4*2)+(3*9)+(2*3)+(1*3)=115
115 % 10 = 5
So 72229-33-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H20O4/c1-8-4-11(16)5-9(2)7-13-14(12(17)6-8)10(3)15(18)19-13/h4,7,11-14,16-17H,3,5-6H2,1-2H3/b8-4+,9-7+/t11-,12-,13-,14-/m1/s1

72229-33-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (3aR,4R,6Z,8S,10Z)-4,8-dihydroxy-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:72229-33-5 SDS

72229-33-5Downstream Products

72229-33-5Relevant academic research and scientific papers

A Thiol-Containing Ester Side Chain in a Sesquiterpene Lactone from Eupatorium mikanioides. Absolute Configuration of Deacetyleupaserrin and Its Congeners

Herz, Werner,Kumar, Narendra,Blount, John F.

, p. 489 - 493 (1980)

Extraction of Eupatorium mikanioides Chapm. yielded a group of 2-hydroxy-8-(acyloxy)-trans,trans-1-(10),4-germacradienolides related to the antileukemic sesquiterpene lactone deacetyleupaserrin (1c) which was also isolated.Absolute configurations were established by X-ray crystallography of one of the constituents (1e) which had an unprecedented thiol-containing ester side chain.The flavone eupatorin was also isolated.

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