A Thiol-Containing Ester Side Chain in a Sesquiterpene Lactone from Eupatorium mikanioides. Absolute Configuration of Deacetyleupaserrin and Its Congeners

DOI: 10.1021/jo01291a023

Source and publish data:

Journal of Organic Chemistry p. 489 - 493 (1980)

Update date:2022-08-04

Topics:

Authors:

Herz, Werner

Kumar, Narendra

Blount, John F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo01291a023

Extraction of Eupatorium mikanioides Chapm. yielded a group of 2-hydroxy-8-(acyloxy)-trans,trans-1-(10),4-germacradienolides related to the antileukemic sesquiterpene lactone deacetyleupaserrin (1c) which was also isolated.Absolute configurations were established by X-ray crystallography of one of the constituents (1e) which had an unprecedented thiol-containing ester side chain.The flavone eupatorin was also isolated.

Full text of DOI:10.1021/jo01291a023

Products guided by the article

Product name:2-Hydroxyeupatolide

Cas No:72229-33-5

R&D Labs maybe for 72229-33-5

Zhejiang Chemline International Co., Ltd.

Contact:+86-571-88062298

Address:Hengdian Industry Area, Dongyang, Zhejiang, China
Shanxi Tongji Pharmaceuticals Co., Ltd.

Contact:+86-359-3024784

Address:Xikuang South Road, Ruicheng County , Shanxi
Shanghai Topchem Co., LTD

website:http://www.shtopchem.com/

Contact:0086-0576-87776998

Address:room no 1608,xuhui business building yude road,xujiahui street, xuhui district
uni source industries limited

Contact:86 21 3772 9386

Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China
Chinese Peptide Company

Contact:86-571-86737118-8689

Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China

Relevant to this article

A General Procedure for Synthesis of N^G-Alkyl, and N^G-Aryl-L-Arginines as Potential Nitric Oxide Synthase Inhibitors

Doi:10.1002/jccs.199800083
(1998)
Design and synthesis of 2-(3-benzo[b]thienyl)-6,7-methylenedioxyquinolin-4- one analogues as potent antitumor agents that inhibit tubulin assembly

Doi:10.1021/jm900456w
(2009)
Kinetics and Activation Parameters for the Reduction of Alkylcyclohexanones by Lithium Tri-tert-butoxyaluminohydride

Doi:10.1021/jo01292a021
(1980)
Chiral Phosphoric Acid-Catalyzed Enantioselective Construction of 2,3-Disubstituted Indolines

Doi:10.1021/acs.orglett.0c03947
(2021)
Br?nsted Base-Induced Rearrangement and Nucleophilic Addition of O/N-Functionalized NHCs and Relative Group 4 Metal Complexes for Ethylene Polymerization Catalysis

Doi:10.1021/acs.organomet.5b00862
(2016)
Direct coupling of indoles with carbonyl compounds: Short, enantioselective, gram-scale synthetic entry into the hapalindole and fischerindole alkaloid families

Doi:10.1021/ja047874w
(2004)

Article Doi