72234-59-4

Upstream product

• 4891-38-7 phenylpropynoic acid methyl ester 
• 873581-55-6 C₁₃H₁₆N₂O₄ 
• 58792-32-8 2-ethoxycarbonylhydrazono-3-phenyl-propionic acid 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 110996-38-8 2-hydroxyimino-3-oxo-3-phenyl-propionic acid methyl ester 
• 1807-69-8 2-diazo-3-oxo-3-phenyl-propionic acid methyl ester 
• 186581-53-3 diazomethane 
• 58792-32-8 α-N-ethoxycarbonylhydrazono-phenylpropionic acid 

Downstream Products

• 58792-15-7 5-Phenyl-1,2,3-thiadiazole-4-carboxylic acid 
• 79036-13-8 5-phenyl-1,2,3-thadiazole-4-carboxyhyrazide 
• 873581-56-7 5-Phenyl-[1,2,3]thiadiazole-4-carbonyl azide 
• 79036-11-6 Methyl-(5-phenyl-[1,2,3]thiadiazol-4-yl)-carbamic acid ethyl ester 
• 79036-12-7 4-ethoxycarbonylamino-5-phenyl-1,2,3-thiadiazole 
• 20851-13-2 dimethyl 2,5-diphenylthiophene-3,4-dicarboxylate 
• 108843-95-4 ((Ξ)-4-methoxycarbonyl-5-phenyl-[1,3]dithiol-2-ylidene)-phenyl-acetic acid methyl ester 

Relevant academic research and scientific papers

HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS

The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, solvates thereof, that bind to Inhibitor of Apoptosis Proteins (IAPs). The compounds of the invention may be used as diagnostic and therapeutic agents in the

Inhibitors of IAP

The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula I: wherein X, Y, A, R1, R2, R3, R4, R4′, R5, R5′, R6 and R6′ are as described herein.

STUDIES ON MESOIONIC COMPOUNDS. XII. SYNTHESIS OF 1,2,3-THIADIAZOLIUM-4-AMINIDE DERIVATIVES AND THEIR CHARACTERIZATION

New mesoionic heterocycles, 1,2,3-thiadiazolium-4-ethoxycarbonylaminides (9 and 10), were prepared by alkylation of 1,2,3-thiadiazoles (5) followed by treatment with base.Compound (9) was hydrolyzed to the hydrochloride of the corresponding 4-imine deriva