722544-85-6

Basic information

• Product Name: 2,2,2-trifluoro-N-(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)acetamide
• Synonyms: 2,2,2-trifluoro-N-(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)acetamide
• CAS NO: 722544-85-6
• Molecular Weight: 330.242
• Mol File: 722544-85-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,2,2-trifluoro-N-(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-N-(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)acetamide(722544-85-6)
• EPA Substance Registry System: 2,2,2-trifluoro-N-(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)acetamide(722544-85-6)

Safety Data

• Hazardous Substances Data: 722544-85-6(Hazardous Substances Data)

Upstream product

• 174891-10-2 (5-amino-2H-pyrazol-3-yl)acetic acid 
• 372-19-0 meta-fluoroaniline 
• 14533-84-7 pentafluorophenyl trifloroacetate 

Downstream Products

• 1258411-40-3 C₁₉H₂₄FN₉O 
• 1258411-41-4 C₁₈H₂₁FN₈O₂ 
• 1258412-08-6 C₁₄H₁₁ClFN₇O 
• 1258411-42-5 C₂₀H₁₇FN₈O 
• 722544-79-8 2-(3-amino-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide 

Relevant articles and documents

Novel quinazoline-containing compound, and intermediate and application thereof

The present invention discloses a quinazoline-containing compound having the formula (IA), (IB) or (IC), or a pharmaceutically acceptable salt or a prodrug molecule thereof. The compound is suitable for use as an Aurora kinase inhibitor and is thus suitable for the treatment of Aurora-mediated diseases characterized by excessive or abnormal cell proliferation, for example, cancer.

PYRAZOLYLAMINO SUBSTITUTED QUINAZOLES FOR THE TREATMENT OF CANCER

The invention provided a compound of formula: (I) for use in the treatment of disease, in particular proliferative diseases such as cancer and for use in the preparation of medicaments for use in the treatment of proliferative diseases; the invention also