722549-29-3

Basic information

• Product Name: 3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-5-ethoxy-5-oxopentanoic acid
• Synonyms: 3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-5-ethoxy-5-oxopentanoic acid
• CAS NO: 722549-29-3
• Molecular Weight: 353.826
• Mol File: 722549-29-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-5-ethoxy-5-oxopentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-5-ethoxy-5-oxopentanoic acid(722549-29-3)
• EPA Substance Registry System: 3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-5-ethoxy-5-oxopentanoic acid(722549-29-3)

Safety Data

• Hazardous Substances Data: 722549-29-3(Hazardous Substances Data)

Upstream product

• 721920-84-9 2-(4-chloro-phenyl)-thiazole-5-carbaldehyde 
• 722549-30-6 4-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]dihydro-2H-pyran-2,6-(3H)-dione 
• 64-17-5 ethanol 

Downstream Products

• 757187-75-0 3-[2-(4-chloro-phenyl)-thiazol-5-yl]-4-{2-[3-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-propyl]-thiazol-4-yl}-butyric acid ethyl ester 
• 722549-28-2 ethyl 6-chloro-3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-5-oxohexanoate 
• 722549-31-7 ethyl 5-chloro-3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-5-oxopentanoate 

Relevant articles and documents

Synthesis of 2,5-thiazole butanoic acids as potent and selective αvβ3 integrin receptor antagonists with improved oral pharmacokinetic properties

We describe a series of 2,5 thiazole containing compounds, which are potent antagonists of the integrin αvβ3 and show selectivity relative to the other integrins, such as αIIbβ 3 and αvβ6. These analogs were demonstrated to have high bioavailability relative to other relative heterocyclic analogs.