72256-95-2

Basic information

• Product Name: 2,4-DIBROMOBENZENESULFONYL CHLORIDE
• Synonyms: 2,4-DIBROMOBENZENESULFONYL CHLORIDE;2,4-DIBROMOBENZENESULPHONYL CHLORIDE;2,4-DIBROMOBENZENESU;2,4-dibroMobenzene-1-sulfonyl chloride;2,4-Dibromobenzenesulfonyl chloride 98%
• CAS NO: 72256-95-2
• Molecular Formula: C₆H₃Br₂ClO₂S
• Molecular Weight: 334.41
• EINECS: -0
• Product Categories: Benzenesulfonyl chloride;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 72256-95-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 82-86 °C(lit.)
• Boiling Point: 128°C 0,2mm
• Flash Point: 128°C/0.2mm
• Appearance: /
• Density: 2.11g/cm3
• Vapor Pressure: 0.00019mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: 2-8°C
• Water Solubility: Insoluble in water.
• Sensitive: Moisture Sensitive
• BRN: 2694058
• CAS DataBase Reference: 2,4-DIBROMOBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIBROMOBENZENESULFONYL CHLORIDE(72256-95-2)
• EPA Substance Registry System: 2,4-DIBROMOBENZENESULFONYL CHLORIDE(72256-95-2)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 72256-95-2(Hazardous Substances Data)

Usage

Uses

2,4-Dibromobenzenesulfonyl chloride is used as pharmaceutical intermediate.

InChI:InChI=1/C6H3Br2ClO2S/c7-4-1-2-6(5(8)3-4)12(9,10)11/h1-3H

Upstream product

• 108-36-1 1,3-dibromobenzene 

Downstream Products

• 1100768-41-9 N-(4-carbamimidoyl-phenyl)-N'-{1-[3-(5-chloro-thiophen-2-yl)-4-(morpholine-4-sulfonyl)-phenyl]-ethyl}-malonamide trifluoroacetate 
• 1100768-46-4 N-(4-carbamimidoyl-phenyl)-N'-{1-[4-(morpholine-4-sulfonyl)-3-thiazol-2-yl-phenyl]-ethyl}-malonamide trifluoroacetate 
• 1100768-44-2 1-[3-(5-chloro-thiophen-2-yl)-4-(morpholine-4-sulfonyl)-phenyl]-ethylamine 
• 1100768-43-1 1-[3-(5-chloro-thiophen-2-yl)-4-(morpholine-4-sulfonyl)-phenyl]-ethanone 
• 1100768-48-6 1-[4-(morpholine-4-sulfonyl)-3-thiazol-2-yl-phenyl]-ethylamine 
• 1100768-42-0 1-[3-bromo-4-(morpholine-4-sulfonyl)-phenyl]-ethanone 
• 1100768-47-5 1-[3-bromo-4-(morpholine-4-sulfonyl)-phenyl]-ethylamine 
• 1583258-79-0 2,4-dibromo-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)benzenesulfonamide 

Relevant articles and documents

CATALYTIC SULFONYLATION OF PHENOL BY STERICALLY HINDERED SULFONYL CHLORIDES

The sulfonylation of phenol by substituted arenesulfonyl chlorides XArSO2Cl in the presence of triethylamine in benzene was studied by potentiometric titration.A linear relation was obtained between the logaritmhs of the catalytic rate constants and the steric constants Eso of the substituents in the sulfonyl chloride.The contribution from the induction and steric effects of the substituents at position2 to the kinetics of the process was assessed.It was concluded that the steric effect plays a predominant role over the induction and resonance effects.