72277-16-8

Upstream product

• 64-17-5 ethanol 
• 72277-01-1 diethyl 1-trimethylsilyloxy-3-phenyl-2-propenylphosphonate 
• 107-08-4 1-iodo-propane 
• 5703-52-6 3-phenylhexanoic acid 
• 14371-10-9 (E)-3-phenylpropenal 
• 54653-25-7 ethyl hex-5-enoate 
• 143-66-8 sodium tetraphenyl borate 
• 27829-72-7 ethyl (E)-hex-2-enoate 
• 591-51-5 phenyllithium 

Relevant academic research and scientific papers

Method To Prepare beta-Functionalized Aliphatic Esters

The invention pertains to a new route to prepare β-functionalized carboxylic acid esters in a one-pot reaction, by reacting an olefinic acid ester in the presence of a catalyst system, comprising a Rh(I)-complex, together with an aryl boron or a diamine a

A method to prepare beta-functionalized aliphatic esters

The invention pertains to a new route to prepare β-functionalized carboxylic acid esters in a one-pot reaction, by reacting an olefinic acid ester in the presence of a catalyst system, comprising a Rh(I)-complex, together with an aryl boron or a diamine a

A METHOD TO PREPARE BETA - FUNCTIONALIZED ALIPHATIC ESTERS

The invention pertains to a new route to prepare β-functionalized carboxylic acid esters in a one-pot reaction, by reacting an olefinic acid ester in the presence of a catalyst system, comprising a Rh(I)-complex, together with an aryl boron or a diamine a

Regioselective synthesis of β-aryl- and β-amino-substituted aliphatic esters by rhodium-catalyzed tandem double-bond migration/conjugate addition

Rhodium-phosphite catalysts were found to effectively mediate double-bond migrations within unsaturated esters. Once the double-bond is in conjugation with the carboxylate group, they also catalyze the Michael addition of carbon and nitrogen nucleophiles.

Potassium trifluoro(organo)borates in rhodium-catalyzed 1,4-additions to α,β-unsaturated esters

This letter describes an efficient and enantioselective conjugate addition of highly stable potassium trifluoro(organo)borates to α,β- unsaturated esters. This reaction, catalyzed by chiral rhodium(I) complexes, affords Michael adducts with high yields an

Rhodium-catalyzed asymmetric 1,4-addition of arylboron reagents to α,β-unsaturated esters

Reaction of arylboron reagents, arylboronic acids or arylborates, which are readily accessible by lithiation of aryl bromides followed by treatment with trimethoxyborane, with α,β-unsaturated esters in the presence of rhodium/(S)-binap catalyst proceeded with high enantioselectivity to give high yields of optically active β-aryl esters of up to 98% ee. The enantioselectivity depends on the steric bulkiness of the ester moiety.

Silyl Phosphites. XVIII. Versatile Utility of α-(Trimethylsilyloxy)-alkylphosphonates as Key Intermediates for Transformation of Aldehydes into Several Carbonyl Derivatives

Carbonyl addition compounds of diethyl trimethylsilyl phosphite (DTMSP) with aldehydes were converted, by treatment with lithium diisopropylamide (LDA) followed by the successive alkylation and alkaline hydrolysis, to carbonyl derivatives involving aldehydes, unsymmetrical ketones, β,γ-unsaturated ketones, and carboxylic acids. β-Substituted carboxylic esters and γ-substituted lactones were prepared by use of the carbonyl addition compounds of DTMSP with α,β-unsaturated aldehydes.

Facile synthesis of β-alkyl-substituted esters from α,β-unsaturated aldehydes

β-Alkyl-substituted carboxylates were synthesized in good yields from α,β-unsaturated aldehydes by using the 1:1 carbonyl adducts with diethyl bis (trimethylsilyl) phosphite.