7229-32-5

Usage

Uses

Used in Pharmaceutical Industry:
2-(prop-2-yn-1-yloxy)cyclohexanol is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be readily incorporated into complex molecular structures, enhancing the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(prop-2-yn-1-yloxy)cyclohexanol serves as a building block for the creation of novel agrochemicals, potentially leading to more effective and targeted pest control agents.
Used in Organic Synthesis:
2-(prop-2-yn-1-yloxy)cyclohexanol is utilized as a versatile precursor in organic synthesis for the preparation of a wide range of compounds, including propargyl ethers and cyclohexenes, which are essential in various chemical reactions and applications.
Used in Antimicrobial Applications:
2-(prop-2-yn-1-yloxy)cyclohexanol is studied for its potential antimicrobial properties, making it a candidate for use in applications requiring the inhibition of microbial growth, such as in medical or industrial settings.
Used in Anti-inflammatory Applications:
Due to its potential anti-inflammatory properties, 2-(prop-2-yn-1-yloxy)cyclohexanol may be employed in the development of treatments for inflammatory conditions, offering a new avenue for therapeutic intervention.

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 107-19-7 propargyl alcohol 
• 930-68-7 cyclohexenone 

Downstream Products

• 51149-92-9 Trimethyl-((1S,2S)-2-prop-2-ynyloxy-cyclohexyloxy)-silane 
• 145350-64-7 <1S*,2S*>-2-(<2-(tributylstannyl)propen-2-yl>oxy)cyclohexan-1-ol 
• 113116-42-0 (R)-2-Prop-2-ynyloxy-cyclohexanone 
• 113116-42-0 α-(prop-2-ynyloxy)cyclohexanone 

Relevant academic research and scientific papers

Novel electrochemical deoxygenation reaction using diphenylphosphinates

The electrochemical reduction of diphenylphosphinate esters leads smoothly and in high yields to the corresponding deoxygenated products. In comparison with the previously developed methodologies, the electrolysis could be performed at lower temperature and with a higher current density, resulting in a shorter reaction time.

Alcoholysis of Epoxides Catalyzed by Tetracyanoethylene and Dicyanoketene Acetals

A typical π-acid tetracyanoethylene and capto-dative olefin dicyanoketene acetals were found to catalyze stereospecific alcoholysis of epoxides at the ambient temperature to 50°C in good yields. Mildness and significant chemoselectivity of the catalysts were demonstrated by intactness of tetrahydropyranyl ether and ethylene acetal groups. A novel regioselectivity associated with anchimeric assistance of the ethereal group on the side chain was observed in the ring opening reaction of the 1,2-disubstituted epoxides.

Free radical cyclization approach to the hexahydrobenzofuran moiety of avermectins: a model study

Hexahydrobenzofurans were prepared through Bu3SnH radical cyclization of propargyloxy cyclohexanone precursors.Good results were obtained for monosubstituted acetylenic derivatives after conversion of the carbonyl group into the corresponding enol ether.U

FREE RADICOL CYCLISATION APPROACH TO THE SOUTHERN MOIETY OF AVERMECTINS.

A hydroxybenzofuran derivative related to part of the avermectin structure has been prepared by a free radical cyclisation.