72293-11-9 Usage
Chemical class
Thiazepine drugs
Molecular structure
Benzothiazepine ring system with a hydroxymethyl group attached to the third carbon
Pharmacological activities
Antipsychotic, anxiolytic, and potential treatment of neurological and psychiatric disorders
Receptor activity
Serotonin and dopamine receptors
Unique properties
Interesting subject of study in medicinal chemistry and drug development
Molecular weight
330.83
Physical state
Solid
Appearance
White or off-white crystalline powder
Solubility
Slightly soluble in water, soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO)
Melting point
198-200°C (392-392.4°F)
Check Digit Verification of cas no
The CAS Registry Mumber 72293-11-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,2,9 and 3 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 72293-11:
(7*7)+(6*2)+(5*2)+(4*9)+(3*3)+(2*1)+(1*1)=119
119 % 10 = 9
So 72293-11-9 is a valid CAS Registry Number.
72293-11-9Relevant academic research and scientific papers
Synthesis of a new potent anti-ulcer and gastric secretory inhibiting agent, (-)-cis-2,3-dihidro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiaze pin-4(5H)-one hydrochloride (BTM-1086), and related compounds
Ohno,Izumi,Mizukoshi,Kato,Hori
, p. 1780 - 1783 (2007/10/02)
(-)-cis-2,3-Dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin-4(5H)-one hydrochloride (BTM-1086) and its analogues, which possessed potent anti-ulcer and gastric secretory inhibiting activities, were synthesized and the structure of these compounds were established on the basis of spectral and chemical evidences.
1,5-Benzothiazepine compounds
-
, (2008/06/13)
Cis or trans-1,5-benzothiazepine compounds represented by the formula (I): STR1 wherein R1 represents a hydrogen atom, a halogen atom, an alkyl group or an alkoxy group and R2 represents a hydrogen atom, an alkyl group or a hydroxyal
