72301-69-0Relevant academic research and scientific papers
Short and simple method of synthesis of some pyrrolo[3,2-b]quinoline derivatives from easily available nitrobenzene derivatives
Wróbel, Zbigniew,Wojciechowski, Krzysztof,Kwast, Andrzej,Gajda, Norbert
body text, p. 2435 - 2438 (2010/11/18)
The Vilsmeier-Hack condensation of ortho-cyanomethylated nitroarenes with N-methylpyrrolidone, followed by cyclization promoted by O,N- bistrimethylsilylacetamide and DBU in DMF led directly to pyrrolo[3,2-b] quinoline derivatives. Georg Thieme Verlag Stuttgart · New York.
Vicarious Nucleophilic Substitution of Hydrogen in Nitroarenes with α-Substituted Nitriles and Esters. Direct α-Cyanoalkylation and α-Carbalkoxyalkylation of Nitroarenes
Makosza, Mieczyslaw,Winiarski, Jerzy
, p. 1494 - 1499 (2007/10/02)
Carbanions generated from alkanenitriles bearing α-chloro, α-OR, or α-SR groups and from aliphatic esters bearing α-SR groups react with mononitroarenes to replace hydrogen atoms of the nitroaromatic ring ortho or para to the nitro group with α-cyanoalkyl or α-carbalkoxyalkyl substituents.The nucleophilic replacement of hydrogen with such carbanions proceeds faster than substitution of halogen ortho or para to the nitro group.
Vicarious Substitution of Hydrogen in Aromatic Nitro Compounds with Acetonitrile Derivatives
Makosza, Mieczyslaw,Winiarski, Jerzy
, p. 1534 - 1535 (2007/10/02)
Carbanions of α-phenoxy and thioalkoxy nitriles substitute hydrogen in the para or ortho position of aromatic nitro compounds, giving nitroarylacetonitriles in a process in which phenolate or thiolate anions are vicarious leaving groups.
