723283-89-4

Basic information

• Product Name: 4-HYDROXY-5-BROMOQUINOLINE
• Synonyms: 4-HYDROXY-5-BROMOQUINOLINE;5-BroMoquinolin-4-ol;5-Bromo-4-quinolinol
• CAS NO: 723283-89-4
• Molecular Formula: C9H6BrNO
• Molecular Weight: 224.05
• Mol File: 723283-89-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 370.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.705±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.49±0.40(Predicted)
• CAS DataBase Reference: 4-HYDROXY-5-BROMOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-5-BROMOQUINOLINE(723283-89-4)
• EPA Substance Registry System: 4-HYDROXY-5-BROMOQUINOLINE(723283-89-4)

Safety Data

• Hazardous Substances Data: 723283-89-4(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-5-Bromoquinoline is a scientific organic compound that falls under the category of bromoquinolines - a subset of quinolines which are aromatic organic compounds. It is represented as C9H6BrNO and it exists in a solid state at room temperature. In terms of its physical description, it is a light-yellow powder and is soluble in chloroform. Interestingly, it absorbs visible light strongly between 200 and 400 nm. 4-HYDROXY-5-BROMOQUINOLINE is widely used in scientific research settings, particularly for the synthesis of more complex molecules in pharmaceuticals or as an intermediate in organic synthesis. However, as with many chemicals, it should be handled with care due to potential hazards it may pose.

Upstream product

• 1391268-61-3 5-bromo-4-oxo-2,3-dihydroquinoline 
• 591-19-5 m-Bromoaniline 
• 723280-91-9 5-(((3-bromophenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Relevant articles and documents

Oxidation method of 4-oxo-2,3-dihydroquinoline compound

The invention discloses an oxidation method of a 4-oxo-2,3-dihydroquinoline compound. The method comprises the following steps: taking the 4-oxo-2,3-dihydroquinoline compound as a raw material; addingan organic solvent, an acidifying agent and an oxidizing agent; performing oxidation reaction at 50-85 DEG C; and after the reaction is finished, performing post-treatment on the reaction liquid to obtain a 4-hydroxyquinoline compound. Various raw materials used by the preparation method disclosed by the invention are simple and easy to obtain, are industrial products and have wide sources and low price; the preparation method is simple, easy to operate and high in product yield; compared with the traditional oxidation method of the 4-oxo-2,3-dihydroquinoline compound, the method disclosed bythe invention has the advantages of being more efficient and simpler in post-treatment; and the method is especially important for the industrialization of the product.

ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES

Aryl substituted imidazoquinoline compounds, according to formula I, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing w or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral., and neoplastic, are disclosed. formula (I): wherein: R is selected from the group consisting of alkyl, alkoxy, hydroxy, and trifluoromethyl;. N is 0 or 1; R3 is selected from the group consisting of: -Z-Ar,-Z-Ar’-Y-R4, -Z-Ar’-X-Y-R4, Z-Ar’-R5, and-Z-Ar'-X-R5; Ar is selected from the group consisting of aryl and heteroaryl both of which can be unsubstituted or can be substituted by one or more substituents independently selected from the group consisting of alkyl, alkenyl, alkoxy, methylenedioxy, haloalkyl, haloalkoxy, halogen, nitro, hydroxy, hydroxyalkyl, mercapto, cyano, carboxy, formyl, aryl, aryloxy, arylalkoxy, heteroaryl, heteroaryloxy, heteroarylalkoxy; heterocyctyl, heterocyclylalkyl, amino, alkylamino, and dialkylamino.