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1-Ethynyl-cyclohexanecarboxylic acid, commonly known as propiolic acid, is a chemical compound characterized by the molecular formula C8H10O2. It is a saturated carboxylic acid featuring a terminal triple bond, which endows it with high reactivity and makes it a versatile building block in organic synthesis and pharmaceutical research. The ethynyl group in its structure contributes to its potential for use in the development of innovative drugs and materials.

72335-58-1

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72335-58-1 Usage

Uses

Used in Organic Synthesis:
1-Ethynyl-cyclohexanecarboxylic acid is used as a key intermediate in organic synthesis for its ability to participate in a variety of chemical reactions, including cross-coupling and addition reactions, facilitating the creation of complex organic molecules.
Used in Pharmaceutical Research:
1-Ethynyl-cyclohexanecarboxylic acid is utilized as a starting material in the development of new drugs due to its unique structure and reactivity, which can be leveraged to design and synthesize bioactive compounds with potential therapeutic applications.
Used in Material Science:
1-Ethynyl-cyclohexanecarboxylic acid is employed as a component in the synthesis of advanced materials, such as polymers and composites, where its reactivity and structural features contribute to the desired properties of the final product.
Used in Chemical Research:
1-Ethynyl-cyclohexanecarboxylic acid serves as a model compound in chemical research to study the reactivity of triple bonds and their influence on the properties of organic molecules, providing insights into the development of new synthetic methods and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 72335-58-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,3,3 and 5 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 72335-58:
(7*7)+(6*2)+(5*3)+(4*3)+(3*5)+(2*5)+(1*8)=121
121 % 10 = 1
So 72335-58-1 is a valid CAS Registry Number.

72335-58-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-ethynyl-1-cyclohexyl-carboxylic acid

1.2 Other means of identification

Product number -
Other names 1-Ethynyl-cyclohexanecarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72335-58-1 SDS

72335-58-1Downstream Products

72335-58-1Relevant academic research and scientific papers

Cobalt-catalyzed carboxylation of propargyl acetates with carbon dioxide

Nogi, Keisuke,Fujihara, Tetsuaki,Terao, Jun,Tsuji, Yasushi

, p. 13052 - 13055 (2015/02/19)

The cobalt-catalyzed carboxylation of propargyl acetates with CO2 (1 atm) is described. The reaction proceeds at room temperature in the presence of Mn powder as a reducing reagent. Various propargyl acetates are converted to the corresponding carboxylic acids in good to high yields.

Pharmaceutically active cyclohexyl compounds and their preparation

-

, (2008/06/13)

The chemical compounds of the invention are useful as the active compound in drugs because of their anticonvulsant and/or antianoxic activity. They have the general formula STR1 wherein Z is a hydroxyl group; a group--OM wherein M is an alkali metal atom or an equivalent atom fraction of an alkaline-earth metal or an amino group such as --NH2, and R is a linear or branched alkyl group containing from 1 to 9 carbon atoms, and optionally substituted by one or more halogen atoms; a linear or branched alkenyl or alkynyl, alkoxyalkyl, or acylalkyl group containing from 2 to 9 carbon atoms and optionally substituted by one or more halogen atoms; an aryl or arylalkyl or aryloxyalkyl group comprising at least one aromatic radical and an alkyl chain having from 1 to 4 carbon atoms.

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