17962-22-0

Basic information

• Product Name: 1-(Trimethylsilylethynyl)cyclohexanol
• Synonyms: 1-(Trimethylsilylethynyl)cyclohexanol;1-[(Trimethylsilyl)ethynyl]-1-cyclohexanol;1-TRIMETHYLSILANYLETHYNYL-CYCLOHEXANOL
• CAS NO: 17962-22-0
• Molecular Formula: C₁₁H₂₀OSi
• Molecular Weight: 196.3614
• Mol File: 17962-22-0.mol
• Article Data: 23

Chemical Properties

• Melting Point: 71.5-72.5 °C
• Boiling Point: 241.9°Cat760mmHg
• Flash Point: 100.1°C
• Appearance: /
• Density: 0.94g/cm³
• Vapor Pressure: 0.00602mmHg at 25°C
• Refractive Index: 1.479
• PKA: 13.85±0.20(Predicted)
• CAS DataBase Reference: 1-(Trimethylsilylethynyl)cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Trimethylsilylethynyl)cyclohexanol(17962-22-0)
• EPA Substance Registry System: 1-(Trimethylsilylethynyl)cyclohexanol(17962-22-0)

Safety Data

• Hazardous Substances Data: 17962-22-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H20OSi/c1-13(2,3)10-9-11(12)7-5-4-6-8-11/h12H,4-8H2,1-3H3

Upstream product

• 111-71-7 heptanal 
• 1066-54-2 trimethylsilylacetylene 
• 61210-52-4 (trimethylsilyl)ethynylmagnesium bromide 
• 108-94-1 cyclohexanone 
• 140149-83-3 B-<2-(trimethylsilyl)ethynyl>-9-borabicyclo<3.3.1>nonane*THF 
• 925-90-6 ethylmagnesium bromide 
• 78-27-3 1-Ethynylcyclohexan-1-ol 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 357428-55-8 1-((phenylselanyl)ethynyl)cyclohexan-1-ol 

Downstream Products

• 855749-01-8 N-(2-(cyclohex-1-en-1-ylethynyl)phenyl)-4-methylbenzenesulfonamide 
• 288254-64-8 2-(cyclohex-1-en-1-ylethynyl)aniline 
• 21983-34-6 1-(bromoethynyl)cyclohex-1-ene 
• 1384432-61-4 N-(cyclohex-1-en-1-ylethynyl)-N-methylmethanesulfonamide 
• 932-66-1 1-cyclohexenyl methyl ketone 
• 54781-35-0 ((1-(cyclohex-1-en-1-yl)vinyl)oxy)trimethylsilane 
• 54678-07-8 1-[(1R,2R)-2-vinylcyclohexyl]ethan-1-one 
• 1399486-91-9 1-(1-(4-bromobenzyl)-1H-1,2,3-triazol-4-yl)cyclohexanol 
• 83027-66-1 (1-benzyl-1H-[1,2,3]triazol-4-yl)-cyclohexylmethanol 

Relevant articles and documents

B--9-borabicyclononane. A New Organoboron Reagent for the Preparation of Propargylic Alcohols

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Metal-free cascade boron–heteroatom addition and alkylation with diazo compounds

Transition metal-catalyzed carbene transfer reaction is one of the most notable advances for C?C bond formation reactionsduring the past decade, which has been widely employed in the preparation of C3-substituted indoles. Here, we described an efficient e

Neighboring Carbonyl Group Assisted Oxyacetoxylation of Propargylic Carboxylates with Retention of Chirality under Metal Free Condition

A metal-free oxyacetoxylation method of primary, secondary and tertiary propargylic carboxylates with retention of chirality was presented. The reaction proceeds through the intramolecular nucleophilic attack of the neighboring carbonyl group on an alkynyliodonium intermediate. The process is general with broad substrate scope and is amenable for application to a variety of propargyl carboxylates including those obtained from natural products. Insight into the mechanistic pathway by isotopic labelling (using H2O18 and D2O) and controlled experiments confirmed. (Figure presented.).

Boron Trichloride-Mediated Synthesis of Indoles via the Aminoboration of Alkynes

We describe an efficient catalyst- and metal-free aminoboration of alkynes to 3-borylated indoles using one of the least expensive boron sources, BCl3. The major dichloro(indolyl)borane products can be used for the in situ construction of usefu