72340-27-3

Upstream product

• 100-47-0 benzonitrile 
• 88-05-1 2,4,6-trimethylaniline 

Downstream Products

• 2904-67-8 N-(2,4,6-trimethylphenyl)-N'-phenylurea 
• 614-28-8 N-benzoylbenzamide 
• 4476-12-4 N-(2,4,6-trimethylphenyl)benzamide 
• 1278597-66-2 2,4,6-trimethyl-N-[phenyl(2,4,6-trimethylphenylamino)methylene]benzamide 
• 1278597-67-3 4-methoxy-N-[phenyl(2,4,6-trimethylphenylamino)methylene]benzamide 
• 67565-31-5 N'-(2,4,6-Trimethylphenyl)-N-<2,2,2,-trifluor-1-(trifluormethyl)ethyliden>benzamidin 

Relevant academic research and scientific papers

Combination of air/moisture/ambient temperature compatible organolithium chemistry with sustainable solvents: Selective and efficient synthesis of guanidines and amidines

Highly-efficient and selective fast addition of in situ generated lithium amides [LiN(H)R] (obtained via an acid-base reaction between n-BuLi and the desired primary amine) into carbodiimides (R-NCN-R) or nitriles (R-CN) has been studied, for the first ti

Vanadium-Catalyzed Oxidative C(CO)-C(CO) Bond Cleavage for C-N Bond Formation: One-Pot Domino Transformation of 1,2-Diketones and Amidines into Imides and Amides

A novel vanadium-catalyzed one-pot domino reaction of 1,2-diketones with amidines has been identified that enables their transformation into imides and amides. The reaction proceeds by dual acylation of amidines via oxidative C(CO)-C(CO) bond cleavage of 1,2-diketones to afford N,N′-diaroyl-N-arylbenzamidine intermediates. In the reaction, these intermediates are easily hydrolyzed into imides and amides through vanadium catalysis. This method provides a practical, simple, and mild synthetic approach to access a variety of imides as well as amides in high yields. Moreover, one-step construction of imide and amide bonds with a long-chain alkyl group is an attractive feature of this protocol.

Copper-catalyzed three-component synthesis of 3-Aminopyrazoles and 4-iminopyrimidines via β-alkynyl-N-sulfonyl ketenimine intermediates

3-Aminopyrazoles and 4-iminopyrimidines were efficiently prepared via copper-catalyzed three-component reactions of butadiynes, sulfonylazides, and hydrazides or imidamides. The reactions were regioselectively approached via the formation of a β-alkynyl-N-sulfonyl ketenimine intermediate which represented a new and effective 1,3-dielectrophilic equivalent in organic synthesis.