72341-38-9

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 5255-17-4 3β-hydroxy-5-cholenoic acid 
• 66414-43-5 3β-(tetrahydro-2H-pyran-2-yloxy)chol-5-en-24-ol 
• 70141-04-7 3β-tetrahydropyranyloxy-24-p-toluenesulfonyloxychol-5-ene 
• 70141-05-8 3β-tetrahydropyranyloxychol-5-en-24-yl cyanide 
• 82008-68-2 methyl 24-hydroxy-3β-tetrahydropyranyloxychol-5-ene-24-carboxylate 
• 98-59-9 p-toluenesulfonyl chloride 
• 60543-47-7 3β-tetrahydropyranyloxy-26,27-dinorcholest-5-en-25-oic acid methyl ester 
• 72341-35-6 (R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-hexanoic acid 
• 72341-36-7 (R)-5-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-iodo-hexanoic acid methyl ester 

Downstream Products

• 72342-07-5 24-fluoro-25-hydroxyvitamin D₃ 

Relevant academic research and scientific papers

Studies on Organic Fluorine Compounds. Part 37. Studies on Steroids. Part 78. Synthesis of 24,24-Difluoro- and 24ξ-Fluoro-25-hydroxyvitamin D3

To clarify the physiological significance of C-24 hydroxylation in vitamin D3 metabolism , vitamin D3 compounds blocked at C-24 by fluorine substituents, namely 24,24-difluoro-25-hydroxyvitamin D3 (1) and 24ξ-fluoro-25-hydroxyvitamin D3 (2) have been synthesized from 3β-hydroxychol-5-en-24-oic acid (13).