5255-17-4

Usage

Uses

Used in Pharmaceutical Industry:
3BETA-HYDROXY-DELTA5-CHOLENIC ACID is used as a therapeutic agent for treating various liver-related conditions, such as neonatal liver disease and cholestasis. Its application is based on its role in bile acid metabolism and its ability to alleviate symptoms associated with these conditions.
Used in Diagnostics:
In the medical field, 3BETA-HYDROXY-DELTA5-CHOLENIC ACID is used as a diagnostic marker to identify and monitor the progression of liver diseases, particularly in newborns and infants. The increased levels of this bile acid in patients with liver disorders help healthcare professionals in diagnosing and managing these conditions effectively.
Used in Research:
3BETA-HYDROXY-DELTA5-CHOLENIC ACID is also utilized in scientific research to study the metabolism of bile acids and their role in various physiological processes. This knowledge contributes to the development of new therapeutic strategies and a better understanding of liver function and related diseases.

InChI:InChI=1/C24H40O6/c1-12(4-7-21(29)30)14-5-6-15-22-16(10-20(28)24(14,15)3)23(2)11-19(27)17(25)8-13(23)9-18(22)26/h12-20,22,25-28H,4-11H2,1-3H3,(H,29,30)

Synthetic route

3β-acetoxy-5-cholenic acid (19462-13-6) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
With sodium hydroxide In methanol for 4h; Ambient temperature;	89.6%

methyl 5-cholenoate (20231-57-6) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
With water; lithium hydroxide In tetrahydrofuran Inert atmosphere;	80%

methyl 3α,6α-ditosyloxy-5β-cholan-24-oate (1184-20-9) + potassium acetate (127-08-2) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
With N,N-dimethyl-formamide Erwaermen des Reaktionsprodukts mit methanol. KOH;

Hyodeoxycholic Acid (83-49-8) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

3β-acetoxy-5α,6β-dibromocholestane (514-50-1) → prasterone acetate (853-23-6) + 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
With chromium(VI) oxide; acetic acid Erwaermen des Reaktionsprodukts mit Zink-Pulver und Essigsaeure und Erwaermen des erhaltenen Reaktionsprodukts mit methanol. Kalilauge;
With chromium(VI) oxide; acetic acid Erwaermen des Reaktionsprodukts mit Zink-Pulver und Essigsaeure und Erwaermen des erhaltenen Reaktionsprodukts mit wss. Natronlauge;

3β-hydroxy-24-nor-chol-5-ene-23,23-dicarboxylic acid (111823-89-3) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
at 200℃;

hyodeoxycholic acid-derivative → 3β-hydroxy-5-cholenoic acid (5255-17-4)

methyl hyodeoxycholate (2868-48-6) → 3β-hydroxy-5-cholenoic acid (5255-17-4) + 4-(10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-pentanoic acid

Conditions	Yield
Stage #1: methyl hyodeoxycholate With pyridine; p-toluenesulfonyl chloride Stage #2: With potassium acetate In N,N-dimethyl-formamide at 110℃; Stage #3: With potassium hydroxide In methanol at 110℃;

3β-acetoxy-Δ5-cholenic aldehyde (86476-29-1) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: 74.2 percent / chromic acid / tetrahydrofuran / 0.17 h / 0 °C 2: 89.6 percent / NaOH (10percent) / methanol / 4 h / Ambient temperature View Scheme

24,24-ethylenedioxy-Δ5-chol-3β,20-diol (86476-21-3) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions

Yield

Multi-step reaction with 6 steps 1: 94.1 percent / pyridine / 14 h / Ambient temperature 2: 88.5 percent / phosphoryl chloride / pyridine / 16 h / Ambient temperature 3: 96.8 percent / H2 / PtO2 / ethanol / 3 h / Ambient temperature 4: 91.7 percent / HCl (10percent) / acetone / 3 h / Ambient temperature 5: 74.2 percent / chromic acid / tetrahydrofuran / 0.17 h / 0 °C 6: 89.6 percent / NaOH (10percent) / methanol / 4 h / Ambient temperature View Scheme

24,24-ethylenedioxy-Δ5-chola-3β-acetate (86476-27-9) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
Multi-step reaction with 3 steps 1: 91.7 percent / HCl (10percent) / acetone / 3 h / Ambient temperature 2: 74.2 percent / chromic acid / tetrahydrofuran / 0.17 h / 0 °C 3: 89.6 percent / NaOH (10percent) / methanol / 4 h / Ambient temperature View Scheme

3β-acetoxy-24,24-ethylenedioxychol-Δ5,20(22)-diene (86476-25-7) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
Multi-step reaction with 4 steps 1: 96.8 percent / H2 / PtO2 / ethanol / 3 h / Ambient temperature 2: 91.7 percent / HCl (10percent) / acetone / 3 h / Ambient temperature 3: 74.2 percent / chromic acid / tetrahydrofuran / 0.17 h / 0 °C 4: 89.6 percent / NaOH (10percent) / methanol / 4 h / Ambient temperature View Scheme

24,24-ethylenedioxy-20-hydroxy-Δ5-chola-3β-acetate (86476-23-5) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
Multi-step reaction with 5 steps 1: 88.5 percent / phosphoryl chloride / pyridine / 16 h / Ambient temperature 2: 96.8 percent / H2 / PtO2 / ethanol / 3 h / Ambient temperature 3: 91.7 percent / HCl (10percent) / acetone / 3 h / Ambient temperature 4: 74.2 percent / chromic acid / tetrahydrofuran / 0.17 h / 0 °C 5: 89.6 percent / NaOH (10percent) / methanol / 4 h / Ambient temperature View Scheme

methyl hyodeoxycholate (2868-48-6) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
Multi-step reaction with 2 steps 2: DMF / Erwaermen des Reaktionsprodukts mit methanol. KOH View Scheme

3β-acetoxy-23,24-bisnor-chol-5-en-22-yl p-toluenesulfonate (120664-97-3) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: xylene / Erwaermen des Reaktionsprodukts mit KOH in Methanol und Isopropylalkohol 2: 200 °C View Scheme

Cholesteryl acetate (604-35-3) → 3β-hydroxy-5-cholenoic acid (5255-17-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: diethyl ether; glacial acetic acid; bromine 2: chromium (VI)-oxide; water containing acetic acid / Erwaermen des Reaktionsprodukts mit Zink-Pulver und Essigsaeure und Erwaermen des erhaltenen Reaktionsprodukts mit wss. Natronlauge View Scheme
Multi-step reaction with 2 steps 1: glacial acetic acid; bromine 2: chromium (VI)-oxide; water containing acetic acid / Erwaermen des Reaktionsprodukts mit Zink-Pulver und Essigsaeure und Erwaermen des erhaltenen Reaktionsprodukts mit wss. Natronlauge View Scheme

3β-hydroxy-5-cholenoic acid (5255-17-4) + acetic anhydride (108-24-7) → 3β-acetoxy-5-cholenic acid (19462-13-6)

Conditions	Yield
With pyridine	100%
With acetic acid

diazomethane (186581-53-3, 908094-01-9) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → methyl 5-cholenoate (20231-57-6)

Conditions	Yield
In tetrahydrofuran; diethyl ether at 20℃; for 0.666667h;	100%
	98%
In diethyl ether; chloroform for 2.5h;	77%

methanol (67-56-1) + 3β-hydroxy-5-cholenoic acid (5255-17-4) + tert-butyldimethylsilyl chloride (18162-48-6) → 3β-(t-butyldimethylsilyloxy)-5-cholenic acid methyl ester (114011-35-7)

Conditions	Yield
Stage #1: methanol; 3β-hydroxy-5-cholenoic acid With toluene-4-sulfonic acid at 60℃; Stage #2: tert-butyldimethylsilyl chloride With 1H-imidazole; dmap In tetrahydrofuran; N,N-dimethyl-formamide at 20℃; for 1h;	99%

tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate (811442-84-9) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → C39H68N2O8

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 3h;	95%

3β-hydroxy-5-cholenoic acid (5255-17-4) → 3β-hydroxy-5α-cholan-24-oic acid (2276-93-9)

Conditions	Yield
With 5%-palladium/activated carbon; hydrogen In tetrahydrofuran; methanol at 20℃; for 48h; Inert atmosphere;	93%
Multi-step reaction with 3 steps 1: hydrogen chloride 2: acetic acid; platinum / Hydrogenation 3: methanol. KOH-solution View Scheme

3β-hydroxy-5-cholenoic acid (5255-17-4) → 3β-hydroxy-5-cholenamide (475102-50-2)

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: With ammonia In tetrahydrofuran; water at 0 - 20℃;	93%

3,4-dihydro-2H-pyran (110-87-2) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → 3β-(Tetrahydropyranyloxy)chol-5-en-24-oic acid 24-tetrahydropyranyl ester (120876-14-4)

Conditions	Yield
With pyridinium p-toluenesulfonate In dichloromethane Ambient temperature;	92%

3β-hydroxy-5-cholenoic acid (5255-17-4) + propargyl alcohol (107-19-7) → 3-hydroxychol-5-en-24-oic acid propargyl ester

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h;	90%

3β-hydroxy-5-cholenoic acid (5255-17-4) + N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) → 5-cholenic acid-3β-ol N-methoxy-N-methylamide (219903-24-9)

Conditions	Yield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Inert atmosphere;	89%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 3h;	85%
Stage #1: 3β-hydroxy-5-cholenoic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In tetrahydrofuran at 20℃; for 1h; Stage #2: N,O-dimethylhydroxylamine*hydrochloride In tetrahydrofuran at 20℃; for 6h;	57%
Stage #1: 3β-hydroxy-5-cholenoic acid With N-ethyl-N,N-diisopropylamine; HATU In tetrahydrofuran at 20℃; for 1h; Stage #2: N,O-dimethylhydroxylamine*hydrochloride In tetrahydrofuran at 20℃; for 6h;	57%

3β-hydroxy-5-cholenoic acid (5255-17-4) + diethylamine (109-89-7) → N,N-diethyl-3β-hydroxy-5-cholenamide

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: diethylamine In tetrahydrofuran at 0 - 20℃;	88%

formic acid (64-18-6) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → 3β-Formato-5-cholenic acid (119748-13-9)

Conditions	Yield
In water at 90 - 95℃; for 3h;	87%

tert-butyl 2-(2-(2-(2-(2-(2-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethylcarbamate (890091-43-7) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → C49H88N2O13

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 3h;	86%

3β-hydroxy-5-cholenoic acid (5255-17-4) + dibutylamine (111-92-2) → N,N-di-n-butyl-3β-hydroxy-5-cholenamide (1450593-71-1)

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: dibutylamine In tetrahydrofuran at 0 - 20℃;	85%

L-β-homo-tryptophan (192003-01-3) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-L-β-homotryptophan

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: L-β-homo-tryptophan In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	85%

3β-hydroxy-5-cholenoic acid (5255-17-4) + C37H76N2O17 → C61H112N2O19

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 3h;	85%

3β-hydroxy-5-cholenoic acid (5255-17-4) + dimethyl amine (124-40-3) → Cholenic acid dimethylamide (79066-03-8)

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: dimethyl amine In tetrahydrofuran at 0 - 20℃;	84%

3β-hydroxy-5-cholenoic acid (5255-17-4) + tetrachloro-N-hydroxyphthalimide tetramethyluronium hexafluorophosphate → C32H37Cl4NO5

Conditions	Yield
With 4-methyl-morpholine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 2h;	84%

L-methionine (63-68-3) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-L-methionine

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: L-methionine In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	83%

3β-hydroxy-5-cholenoic acid (5255-17-4) + methyl iodide (74-88-4) → methyl 5-cholenoate (20231-57-6)

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	82%
With diethyl ether; silver(l) oxide
With sodium hydroxide 1.) MeOH, 2.) DMF; Yield given. Multistep reaction;

3β-hydroxy-5-cholenoic acid (5255-17-4) + propargyl alcohol (107-19-7) → prop-2-ynyl 4-(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 18h;	82%

3β-hydroxy-5-cholenoic acid (5255-17-4) + di-n-propylamine (142-84-7) → N,N-di-n-propyl-3β-hydroxy-5-cholenamide (1450593-70-0)

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: di-n-propylamine In tetrahydrofuran at 0 - 20℃;	82%

3β-hydroxy-5-cholenoic acid (5255-17-4) + D-tryptophan (153-94-6) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-D-tryptophan

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: D-tryptophan In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	82%

3β-hydroxy-5-cholenoic acid (5255-17-4) + methylamine (74-89-5) → Cholenic acid monomethylamide

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: methylamine In tetrahydrofuran at 0 - 20℃;	81%

L-phenylalanine (63-91-2) + 3β-hydroxy-5-cholenoic acid (5255-17-4) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-L-phenylalanine

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: L-phenylalanine In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	81%

3β-hydroxy-5-cholenoic acid (5255-17-4) + L-1-naphthylalanine (55516-54-6) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-L-3-(α-naphthyl)alanine

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: L-1-naphthylalanine In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	81%

3β-hydroxy-5-cholenoic acid (5255-17-4) + 5-bromo-DL-tryptophan (6548-09-0, 25197-99-3, 93299-40-2) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-5-bromo-L-tryptophan

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: 5-bromo-DL-tryptophan In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	80%

3β-hydroxy-5-cholenoic acid (5255-17-4) + L-Tryptophan (73-22-3) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-L-tryptophan

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: L-Tryptophan In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	79%

3β-hydroxy-5-cholenoic acid (5255-17-4) + 1-methyl-L-tryptophan (21339-55-9, 26988-72-7, 110117-83-4) → N-(3β-hydroxy-Δ5-cholen-24-oyl)-1-methyl-L-tryptophan

Conditions	Yield
Stage #1: 3β-hydroxy-5-cholenoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.416667h; Inert atmosphere; Stage #2: 1-methyl-L-tryptophan In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere; chemoselective reaction;	77%

Upstream product

• 2868-48-6 methyl hyodeoxycholate 
• 20231-57-6 methyl 5-cholenoate 
• 604-35-3 Cholesteryl acetate 
• 120664-97-3 3β-acetoxy-23,24-bisnor-chol-5-en-22-yl p-toluenesulfonate 
• 86476-23-5 24,24-ethylenedioxy-20-hydroxy-Δ⁵-chola-3β-acetate 
• 86476-25-7 3β-acetoxy-24,24-ethylenedioxychol-Δ^5,20(22)-diene 
• 86476-27-9 24,24-ethylenedioxy-Δ⁵-chola-3β-acetate 
• 86476-21-3 24,24-ethylenedioxy-Δ⁵-chol-3β,20-diol 
• 86476-29-1 3β-acetoxy-Δ⁵-cholenic aldehyde 
• 19462-13-6 3β-acetoxy-5-cholenic acid 
• 111823-89-3 3β-hydroxy-24-nor-chol-5-ene-23,23-dicarboxylic acid 
• 514-50-1 3β-acetoxy-5α,6β-dibromocholestane 
• 83-49-8 Hyodeoxycholic Acid 
• 1184-20-9 methyl 3α,6α-ditosyloxy-5β-cholan-24-oate 

Downstream Products

• 69776-17-6 3β-hydroxy-5-cholen-24-oyl-glycin 
• 54668-67-6 3β,24-dihydroxychol-5-ene 
• 1452-29-5 3-oxo-4-cholenic acid 
• 20231-57-6 methyl 5-cholenoate 
• 79066-03-8 N,N-dimethyl-3β-hydroxy-5-cholenamide 
• 115567-36-7 1α,3β-bis(methoxymethoxy)-24-p-toluenesulfonyloxychol-5-ene 
• 106372-51-4 1α,25-dihydroxy-26,27-diethylvitamin D₃ 
• 97473-92-2 1α,25-dihydroxy-26,27-dimethylvitamin D₃ 
• 106372-44-5 1α-dihydroxy-26,27-dimethylvitamin D₃ 
• 84529-86-2 (20R)-3β-(tert-butyldimethylsilyloxy)-24-hydroxy-25,26,27-trisnorcholest-5-ene 
• 114011-35-7 3β-(t-butyldimethylsilyloxy)-5-cholenic acid methyl ester 
• 186139-68-4 7α-(Benzyloxy)-3β-(1,5,10-triazadecyl)cholestan-24ξ-ol 
• 166896-86-2 7α-(Benzyloxy)-3ξ-<5,10-bis(tert-butoxycarbonyl)-1,5,10-triazadecyl>-24ξ-<(tert-butyldimethylsilyl)oxy>-cholestane 

Relevant academic research and scientific papers

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