72345-99-4

Basic information

• Product Name: (+/-)-(1RS,2SR,3RS,5RS)-3-(5-amino-6-chloro-pyrimidin-4-yl-amino)-5-hydroxymethyl-cyclopentane-1,2-diol
• CAS NO: 72345-99-4
• Molecular Weight: 274.707
• Mol File: 72345-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-(1RS,2SR,3RS,5RS)-3-(5-amino-6-chloro-pyrimidin-4-yl-amino)-5-hydroxymethyl-cyclopentane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-(1RS,2SR,3RS,5RS)-3-(5-amino-6-chloro-pyrimidin-4-yl-amino)-5-hydroxymethyl-cyclopentane-1,2-diol(72345-99-4)
• EPA Substance Registry System: (+/-)-(1RS,2SR,3RS,5RS)-3-(5-amino-6-chloro-pyrimidin-4-yl-amino)-5-hydroxymethyl-cyclopentane-1,2-diol(72345-99-4)

Safety Data

• Hazardous Substances Data: 72345-99-4(Hazardous Substances Data)

Upstream product

• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 62138-01-6 (+/-)-(1α,2α,3β,5β)-3-amino-5-(hydroxymethyl)-1,2-cyclopentanediol 

Downstream Products

• 72346-00-0 (+/-)-9-<2α,3α-dihydroxy-4α-(hydroxymethyl)cyclopent-1α-yl>adenine 
• 49815-23-8 (+/-)-9-<β-(2α,3α-dihydroxy-4β-(hydroxymethyl)cyclopentyl)>-6-chloropurine 

Relevant articles and documents

Biocatalytical Transformations- VI. The 4-Acetamido-cyclopent-2-ene Carboxylate Route Revisited: Synthesis of (+)- and (-)-Aristeromycin

Enantiomerically pure (+)-as well as (-)-aristeromycin can be synthesized starting from (+)- or (-)-butyl (or hexyl) 4-acetamido-cyclopent-2-ene carboxylate; these carboxylates are easily obtained from their corresponding racemates by hydrolysis with the lipase from Candida rugosa.