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62138-01-6

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62138-01-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 62138-01-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,1,3 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 62138-01:
(7*6)+(6*2)+(5*1)+(4*3)+(3*8)+(2*0)+(1*1)=96
96 % 10 = 6
So 62138-01-6 is a valid CAS Registry Number.

62138-01-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-amino-5-(hydroxymethyl)cyclopentane-1,2-diol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:62138-01-6 SDS

62138-01-6Relevant articles and documents

Synthesis of 4a-Carba-d-lyxofuranose Derivatives and Their Evaluation as Inhibitors of GH38 α-Mannosidases

Zaji?ková, Mária,Monco?, Ján,?esták, Sergej,Kóňa, Juraj,Koó?, Miroslav,Bella, Maro?

, p. 1114 - 1124 (2019/01/24)

A synthetic approach to 4a-carba-d-lyxofuranose derivatives starting from d-lyxose is described. The protected 4a-carba-β-d-lyxofuranose was employed as the key intermediate for the synthesis of 4a-carba-d-lyxofuranose derivatives including novel 1-amino-1-deoxy-4a-carba-d-lyxofuranoses. Synthesized 4a-carba-d-lyxofuranoses were evaluated as inhibitors of GH38 α-mannosidases, namely, the Golgi (GMIIb) and lysosomal (LManII) α-mannosidases from Drosophila melanogaster and commercial Jack bean α-mannosidase (JBMan) from Canavalia ensiformis. The biochemical evaluation revealed that only 1-amino-1-deoxy-4a-carba-β-d-lyxofuranose exhibited reasonable inhibitory activity against GMIIb (IC50 = 200 μm). In addition, the results of biological evaluation were discussed by means of molecular modelling.

Synthesis of carbocyclic nucleosides from 2-azabicyclo[2.2.1]hept-5-en-3-ones: Sodium borohydride-mediated carbon-nitrogen bond cleavage of five- and six-membered lactams

Katagiri,Muto,Nomura,Higashikawa,Kaneko

, p. 1112 - 1122 (2007/10/02)

Various carbocyclic ribofuranosyl nucleosides were stereoselectively synthesized through a small number of steps from 2-azabicyclo[2.2.1]hept-5-en-3-ones by the use of sodium borohydride-mediated C-N bond cleavage as a key step. Ready availability of a no

Synthesis of cyclopentane analogs of (2'- and 3'-deoxy-erythro-pentofuranosyl and ribofuranosyl)-2-thiouracil nucleosides

Hronowski, Lucjan J. J.,Szarek, Walter A.

, p. 1620 - 1629 (2007/10/02)

Three new carbocyclic analogus of nucleosides having the 2-thiouracil base have been synthesized.The cyclopentyl groups in these nucleosides are (+/-)- (see 31), (+/-)- (see 32) and (+/-)- (see 33).The nucleosides were prepared by coupling the appropriate hydroxy derivatives of cis-3-aminocyclopentanemethanol with 3-ethoxypropenoyl isothiocyanate (21) followed by cyclization in 15 N aqueous ammonia to give the 2-thiouracil nucleosides.In addition a modified and shortenedsynthetic route is described for the synthesys of (+/-)-(1β,2α,3α,4β)-4-amino-2,3-dihydroxy-cyclopentanemethanol (19).The (1)H nmr spectra at 200 MHz of all of the synthetic intermediates, the 2-thiouracil nucleosides, and of the corresponding carbocyclic analogs of uracil nucleosides are discussed.It is shown that each nucleoside has a characteristically unique (1)H nmr spectrum and that in general the protons in the sulfur-containing compounds resonate at lower filds than those in the corresponding oxygen-containing compounds.The magnitude of this downfield shift is inversely related to the number of bonds separating a particular proton from the sulfur atom.

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