7236-72-8

Usage

Uses

Used in Pharmaceutical Industry:
1-(but-3-en-1-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is used as an intermediate in the synthesis of pharmaceutical drugs for its ability to contribute to the development of new medications with potentially beneficial properties. Its unique structure allows for the creation of a wide range of compounds that can be tailored for specific therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(but-3-en-1-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is used as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its structural versatility enables the development of novel compounds that can be applied to enhance crop protection and increase agricultural productivity.
Used in Chemical Research:
1-(but-3-en-1-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is also utilized in chemical research as a versatile building block for designing and creating new compounds with potentially beneficial properties. Its unique structure allows researchers to explore various applications in different fields, including materials science, catalysis, and environmental chemistry.

Upstream product

• 5162-44-7 1-bromo-4-butene 
• 65-71-4 thymin 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 

Downstream Products

• 1609235-07-5 (4-phenyldimethylsilyl)butylthymine 

Relevant academic research and scientific papers

Biomimetic polyorganosiloxanes: Model compounds for new materials

The chemistry of N-organosilylalkyl-substituted heterocyclic bases (thymine, adenine and cytosine) is described, covering the structures of model compounds, the synthesis of substituted oligo-siloxanes and a preliminary report of the synthesis of a poly(organosiloxane) with pendant N-alkyl(heterocycle) functionalities. N-Alkenylthymines CH2CH(CH2)nT (T = thymine, n = 1 (1), 2 (2), 3 (3)) have been prepared and 2 hydrosilylated to form PhMe2Si(CH2)4T (5). Alternatively, 5 was prepared by reaction of PhMe2Si(CH2)4Br (6) with (O,O-SiMe3)2T, a method which has also been used to prepare PhMe2Si(CH2)4A (7) and PhMe 2Si(CH2)4C (8) (A = adenine, C = cytosine). Model di- and tri-siloxanes [Br(CH2)4(Me) 2Si]2O (10), Me3SiOSi(Me)2(CH 2)4Br (11), PhMe2SiOSi(Me)2(CH 2)4Br (12) and (Me3SiO)2(Me) Si(CH2)4Br (13) have been prepared by hydrosilylation of H2CC(H)(CH2)4Br with an appropriate hydrosiloxane and used to prepare Me3SiO(Me)2Si(CH 2)4T (14), Me3SiO(Me)2Si(CH 2)4A (15) (both from 11), and (Me3SiO) 2(Me)Si(CH2)4T (16), (Me3SiO) 2(Me)Si(CH2)4A (17) (both from 13). 10 reacts with thymine to give a mixture of the pyrimidocyclophane cyclo-T-N,N-[(CH 2)4(Me)2Si]2O (19) and [T(CH 2)4Si(Me)2]2O (20), while cytosine reacts similarly to form cyclo-C-N,N-[(CH2)4(Me) 2Si]2O (21; as an imine) and [C(CH2) 4Si(Me)2]2O (22); adenine only generates [A(CH2)4Si(Me)2]2O (18) in an analogous synthesis. Using a related protocol, polymeric {[MeSi(O)(CH 2)4Br]2[Me2SiO]98} n (23) has been converted to {[MeSi(O)(CH2) 4T]2[Me2SiO]98}n (24) and {[MeSi(O)(CH2)4A]2[Me2SiO] 98}n (25). The structures of 4, 5, 8, 19 and 21, along with a 2:1 adduct of 5 with Ni(dithiobiuret)2 (9) are reported. This journal is the Partner Organisations 2014.

INTRAMOLECULAR PHOTOCYCLOADDITION OF N1-(ω-ALKENYL)PYRIMIDINES: FORMATION OF DIAZATRICYCLODIONES

Irradiation of N1-(ω-alkenyl)pyrimidines in a CH3CN solution gave parallel cycloadducts, diazatricyclodiones, as the sole photoproduct.