7237-40-3Relevant academic research and scientific papers
Intramolecular Diels-Alder Cycloaddition Approach toward the cis-Fused Δ5,6-Hexahydroisoindol-1-one Core of Cytochalasins
Xu, Jingjing,Lin, Benguo,Jiang, Xiuqing,Jia, Zejun,Wu, Jinlong,Dai, Wei-Min
supporting information, p. 830 - 834 (2019/01/26)
Synthesis of the cis-fused Δ5,6-hexahydroisoindol-1-one core of cytochalasins B2-B5, K, Z8, Z9, Z12-Z15, and Z17 has been established starting from an intramolecular D
Asymmetric synthesis of α-chiral ketones by the reduction of enones with baker's yeast
Kawai, Yasushi,Hayashi, Motoko,Tokitoh, Norihiro
, p. 3007 - 3013 (2007/10/03)
Baker's yeast-mediated asymmetric reduction of α,β-unsaturated ketones (enones) having a pyridyl ring affords the corresponding optically active α-substituted ketones (α-chiral ketones) with excellent stereoselectivity. The position of the heteroatom, as well as the bulk of the α-substituent, plays an important role in governing the stereoselectivity in the reduction of a carbon-carbon double bond.
