72393-99-8

Basic information

• Product Name: anhydroecgonine acid chloride
• Synonyms: anhydroecgonine acid chloride
• CAS NO: 72393-99-8
• Molecular Weight: 185.653
• Mol File: 72393-99-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: anhydroecgonine acid chloride(CAS DataBase Reference)
• NIST Chemistry Reference: anhydroecgonine acid chloride(72393-99-8)
• EPA Substance Registry System: anhydroecgonine acid chloride(72393-99-8)

Safety Data

• Hazardous Substances Data: 72393-99-8(Hazardous Substances Data)

Upstream product

• 481-37-8 ecgonine 
• 53-21-4 (-)-cocaine hydrochloride 
• 74242-55-0 anhydroecgonine hydrochloride 

Downstream Products

• 196295-98-4 (1R,2S,3S,5S)-3-(3,4-Dichloro-phenyl)-8-prop-2-ynyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester 
• 146725-34-0 O-456 
• 387357-14-4 N-[4-(3-iodo-4-aminophenyl)butyl]-2β-carbomethoxy-3β-(4-chlorophenyl)tropane 
• 387357-12-2 N-[4-(4-nitrophenyl)butyl]-2β-carbomethoxy-3β-(4-chlorophenyl)tropane 
• 387357-13-3 N-[4-(4-aminophenyl)butyl]-2β-carbomethoxy-3β-(4-chlorophenyl)tropane 
• 146725-33-9 O 374 
• 130342-80-2 2β-carbomethoxy-3β-(4-chlorophenyl)tropane 

Relevant articles and documents

Synthesis of iodinated and radioiodinated (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(3',4'-dichlorophenyl) notropane (β-CDIT): A ligand for the dopamine transporter

The synthesis of (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(3',4'-dichlorophenyl) nortropane (β-CDIT) and its radioiodinated analogues is described. Three different synthetic methods are reported for the preparation of (E)-N-[3-(tributylstannyl)-2-enyl]-2β-carbomethoxy-3β-(3', 4'-dichlorophenyl) nortropane, which was iododestannylated for the preparation of the corresponding iodinated derivative. We also report the radiolabelling of β-CDIT with 125I or 123I that could be used for in vitro and in vivo exploration of the dopamine transporter.

The synthesis of deuterium-labelled cocaine, cocaethylene and metabolites

We describe the syntheses of benzoylecgonine (1,1,1-2H3)methyl ester [(2H3) cocaine], (2H5)benzoylecgonine, (2H5)benzoylecgonine methyl ester [(2H5/su