724-92-5

Basic information

• Product Name: N-cicloesil-α-ossofenilacetamide
• Synonyms: N-cicloesil-α-ossofenilacetamide
• CAS NO: 724-92-5
• Molecular Weight: 231.294
• Mol File: 724-92-5.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: N-cicloesil-α-ossofenilacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cicloesil-α-ossofenilacetamide(724-92-5)
• EPA Substance Registry System: N-cicloesil-α-ossofenilacetamide(724-92-5)

Safety Data

• Hazardous Substances Data: 724-92-5(Hazardous Substances Data)

Upstream product

• 931-53-3 Cyclohexyl isocyanide 
• 2397-26-4 N,N-dimethyl(chlorophenylmethylene)ammonium chloride 
• 98-88-4 benzoyl chloride 
• 41182-88-1 N-butyl-benzimidoyl chloride 
• 4421-48-1 N-cyanocyclohexylamine 
• 611-73-4 Benzoylformic acid 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 108-91-8 cyclohexylamine 
• 4998-76-9 cyclohexylamine hydrochloride 
• 98-86-2 acetophenone 
• 860460-70-4 N-cyclohexyl-5-methyl-2-phenylimidazo[1,2-a]pyridine-3-amine 
• 614-16-4 Benzoylacetonitrile 
• 24155-34-8 2-(1H-imidazol-1-yl)-1-phenylethanone 

Downstream Products

• 10321-39-8 5'-phenylcyclohexanespiro-2'-oxazolidin-4'-one 
• 78523-81-6 N-(1-methoxycyclohexyl)mandelamide 
• 4410-31-5 (RS)-mandelamide 
• 108-94-1 cyclohexanone 
• 62448-60-6 N-cyclohexyl-2-hydroxy-2-phenylethanamide 
• 743-99-7 N-<α-Phenylhydrazono-phenylacetyl>-cyclohexylamin 
• 10264-08-1 N-cyclohexyl-2-phenyl-acetamide 
• 123149-97-3 2-<(Acetyl)(phenyl)hydrazono>-N-cyclohexyl-2-phenylacetamid 
• 743-99-7 N-Cyclohexyl-2-phenyl-2-(phenyl-hydrazono)-acetamide 

Relevant articles and documents

Selective electrochemical oxidation of aromatic hydrocarbons and preparation of mono/multi-carbonyl compounds

A selective electrochemical oxidation was developed under mild condition. Various mono-carbonyl and multi-carbonyl compounds can be prepared from different aromatic hydrocarbons with moderate to excellent yield and selectivity by virtue of this electrochemical oxidation. The produced carbonyl compounds can be further transformed into α-ketoamides, homoallylic alcohols and oximes in a one-pot reaction. In particular, a series of α-ketoamides were prepared in a one-pot continuous electrolysis. Mechanistic studies showed that 2,2,2-trifluoroethan-1-ol (TFE) can interact with catalyst species and generate the corresponding hydrogen-bonding complex to enhance the electrochemical oxidation performance. [Figure not available: see fulltext.]

Synthesis of aliphatic α-ketoamides from α-substituted methyl ketones: Via a Cu-catalyzed aerobic oxidative amidation

α-Ketoamides are an important key functional group and have been used as versatile and valuable intermediates and synthons in a variety of functional group transformations. Synthetic methods for making aryl α-ketoamides as drug candidates have been greatly improved through metal-catalyzed aerobic oxidative amidations. However, the preparation of alkyl α-ketoamides through metal-catalyzed aerobic oxidative amidations has not been reported because generating α-ketoamides from aliphatic ketones with two α-carbons theoretically provides two distinct α-ketoamides. Our strategy is to activate the α-carbon by introducing an N-substituent at one of the two α-positions. The key to this strategy is how heterocyclic compounds such as triazoles and imidazoles affect the selectivity of the synthesis of the alkyl α-ketoamides. From this basic concept, and by optimizing the reaction and elucidating the mechanism of the synthesis of aryl α-ketoamides via a copper-catalyzed aerobic oxidative amidation, we prepared fourteen aliphatic α-ketoamides in high yields (48-84%). This journal is

Synthesis method of alpha-ketoamide compound

The invention discloses a synthesis method of an alpha-ketoamide compound. The preparation method comprises the following steps of: taking an isocyanate compound as shown in a formula I and a benzoylformic acid compound as shown in a formula II as raw mat