72409-27-9Relevant academic research and scientific papers
HIGH YIELD SELECTIVE 3'-SILYLATION OF RIBONUCLEOSIDES
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 5243 - 5246 (1981)
Prucedures have been developed which permit the highly selective silylation of the 3'-hydroxyl of ribonucleosides to produce 3',5'-diprotected derivatives in high yields.
The S,X-acetals in nucleoside chemistry: II. The synthesis of 3′-O-methylthiomethylribonucleosides
Pechenov,Zavgorodny,Shvets,Miroshnikov
, p. 407 - 413 (2007/10/03)
3′-O-Methylthiomethyl derivatives of ribonucleosides were synthesized from the selectively protected nucleosides by the action of a dimethyl sulfide-benzoyl peroxide mixture in acetonitrile or a dimethyl sulfoxide-acetic anhydride-acetic acid mixture.
Nucleotides, XVIII. Synthesis and Properties of (tert-Butyldimethylsilyl)guanosines, Guanosine-3'-Phosphotriesters and Guanosine-containing Oligonucleotides
Flockerzi, Dieter,Schlosser, Wilhelm,Pfleiderer, Wolfgang
, p. 2069 - 2085 (2007/10/02)
Silylation of N2-benzoyl- (1) and N2-isobutyrylguanosin (2) by tert-butyldimethylsilyl chloride led to the various mono-, di- and tri-O-tert-butyldimethylsilyl derivatives 3-15.The synthesis of 2'- (24-31) and 3'-phosphotriesters (16
New catalists and procedures for the dimethoxytritylation and selective silylation of ribonucleosides
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 1106 - 1113 (2007/10/02)
Procedures have been developed for the selective formation of (a) 2',5'-silylated ribonucleosides and (b) 3',5'-silylated ribonucleosides.These procedures also permit the selective silylation at either the 2'- or 3'-position of dimethoxytritylated ribonuc
NITRATE ION AS CATALYST FOR SELECTIVE SILYLATIONS OF NUCLEOSIDES
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 4775 - 4778 (2007/10/02)
Nitrate ion has been found to have a remarkable effect on the selectivity of silylation of ribonucleosides using the t-butyldimethylsilyl group.
ISOMERIZATION OF tert-BUTYLDIMETHYLSILYL PROTECTING GROUPS IN RIBONUCLEOSIDES
Ogilvie, Kelvin K.,Entwistle, Douglas W.
, p. 203 - 210 (2007/10/02)
The tert-butyldimethylsilyl group undergoes isomerization between O-2' and O-3' in ribonucleosides in solution.Isomerization is most rapid in protic solvents and extremely slow in such solvents as dry dimethyl sulfoxide, pyridine, oxolane, chloroform, or
