72450-34-1Relevant articles and documents
Aerobic α-hydroxylation of β-keto esters and amides by co-catalysis of SmI3 and I2 under mild base-free conditions
Yu, Shun-Ming,Cui, Kai,Lv, Fei,Yang, Zhen-Yu,Yao, Zhu-Jun
supporting information, p. 2818 - 2821 (2016/06/09)
A clean base-free α-hydroxylation of β-keto esters and amides has been developed, in which air was used as the oxygen source and SmI3 and I2 were applied as the catalysts, affording the corresponding α-hydroxylated 1,3-dicarbonyl pro
Cerium-catalyzed α-hydroxylation reactions of α-cyclopropyl β-dicarbonyl compounds with molecular oxygen
Christoffers, Jens,Kauf, Thomas,Werner, Thomas,Roessle, Michael
, p. 2601 - 2608 (2007/10/03)
Three α-cyclopropyl β-dicarbonyl compounds have been used as probes for α-radicals as electrophilic reaction intermediates in a cerium-catalyzed α-hydroxylation reaction with molecular oxygen. Since the cyclopropyl group did not ring-open to products with a butenyl moiety, but was retained in the products, a localized unpaired electron at the α position can be excluded during the course of the reaction. The α-cyclopropyl- substituted substrates were prepared by aldol or Claisen reactions. Other substrates with α-methyl, α-isopropyl, and α-tert-butyl substituents were prepared and converted under the α-hydroxylation conditions in order to estimate steric influences on the yield of the reaction. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
Synthesis of 2-Hydroxy-3-oxocarboxylic Esters From the Corresponding α,β-Unsaturated Esters by a Simple One-Step Procedure
Crout, D. H. G.,Rathbone, D. L.
, p. 40 - 42 (2007/10/02)
A convenient one-step synthesis of 2-alkyl-2-hydroxy-3-oxocarboxylic esters by potassium permanganate oxidation of the corresponding readily available α,β-unsaturated esters is described.Preparation of the latter by the phosphonate modification of the Wit
