724733-52-2Relevant academic research and scientific papers
Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs
Johansson, Per-Ola,Chen, Yantao,Belfrage, Anna Karin,Blackman, Michael J.,Kvarnstr?m, Ingemar,Jansson, Katarina,Vrang, Lotta,Hamelink, Elizabeth,Hallberg, Anders,Rosenquist, ?sa,Samuelsson, Bertil
, p. 3353 - 3366 (2007/10/03)
Picomolar to low nanomolar inhibitors of the two aspartic proteases plasmepsin (Plm) I and II, from the malaria parasite Plasmodium falciparum, have been identified from sets of libraries containing novel statine-like templates modified at the amino and c
