724787-53-5 Usage
Uses
Used in Organic Synthesis:
(3R,4R)-Benzyl 4-(tert-butoxycarbonylamino)-3-hydroxypiperidine-1-carboxylate is used as a protecting group in organic synthesis for [application reason]. The tert-butoxycarbonyl group can be selectively removed under mild conditions, facilitating the synthesis of more complex molecules.
Used in Drug Development:
(3R,4R)-Benzyl 4-(tert-butoxycarbonylamino)-3-hydroxypiperidine-1-carboxylate is used as a building block or intermediate in drug development for [application reason]. Its versatile structure and functional groups can be modified to create new pharmaceutical compounds with potential therapeutic properties.
Used in Chemical Reactions:
(3R,4R)-Benzyl 4-(tert-butoxycarbonylamino)-3-hydroxypiperidine-1-carboxylate is used as a reactant in various chemical reactions, such as esterification and amidation, for [application reason]. The hydroxy and carboxylate functional groups allow for the formation of new chemical bonds and the synthesis of diverse products.
Check Digit Verification of cas no
The CAS Registry Mumber 724787-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,4,7,8 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 724787-53:
(8*7)+(7*2)+(6*4)+(5*7)+(4*8)+(3*7)+(2*5)+(1*3)=195
195 % 10 = 5
So 724787-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H26N2O5/c1-18(2,3)25-16(22)19-14-9-10-20(11-15(14)21)17(23)24-12-13-7-5-4-6-8-13/h4-8,14-15,21H,9-12H2,1-3H3,(H,19,22)/t14-,15-/m1/s1
724787-53-5Relevant academic research and scientific papers
Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases
Miles, Timothy J.,Axten, Jeffrey M.,Barfoot, Christopher,Brooks, Gerald,Brown, Pamela,Chen, Dongzhao,Dabbs, Steven,Davies, David T.,Downie, David L.,Eyrisch, Susanne,Gallagher, Timothy,Giordano, Ilaria,Gwynn, Michael N.,Hennessy, Alan,Hoover, Jennifer,Huang, Jianzhong,Jones, Graham,Markwell, Roger,Miller, William H.,Minthorn, Elizabeth A.,Rittenhouse, Stephen,Seefeld, Mark,Pearson, Neil
, p. 7489 - 7495 (2012/02/04)
We have identified a series of amino-piperidine antibacterials with a good broad spectrum potency. We report the investigation of various subunits in this series and advanced studies on compound 8. Compound 8 possesses good pharmacokinetics, broad spectrum antibacterial activity and demonstrates oral efficacy in a rat lung infection model.
