72487-70-8Relevant academic research and scientific papers
Synthesis of highly branched perfluoroolefins that are super-congested via multi-substitution of trifluoromethyl groups: Trifluoromethylation of hexafluoropropene trimers with Ruppert-Prakash reagent
Ono, Taizo
, p. 128 - 134 (2017)
The reaction of hexafluoropropene trimers with Ruppert-Prakash (CF3SiMe3) reagent gave highly congested perfluoroolefins such as the mono-trifluoromethylation products F-2,4-dimethyl-3-isopropyl-2-pentene (P1) and E- and Z-forms of F-4,4-dimethyl-3-isopropyl-2-pentene (2E and 2Z), and the bis-trifluoromethylation product F-2,4,4-trimethyl-3-isopropyl-2-pentene (3). The E-form of 2 was also comprised of two rotamers. Various aprotic polar solvents were surveyed for this reaction, and it was found that the aprotic solvent DMI has a unique solvent effect to selectively give the mono-trifluoromethylated perfluoroolefin P1, a precursor for the persistent perfluoroalkyl radical F-3-isopropyl-2,4-dimethyl-3-pentyl, in very high yield.
