7251-21-0Relevant academic research and scientific papers
Synthesis and antioxidant activity of thymol and carvacrol based Schiff bases
Beena,Kumar, Deepak,Rawat, Diwan S.
, p. 641 - 645 (2013/03/13)
Thymol and carvacrol are well known antioxidants found in the extract of the plants of thyme species. The Schiff bases of 2-iso-propyl-5-methyl-phenol (thymol/1a), 2-tert-butyl-5-methyl-phenol (1b) and 5-iso-propyl-2-methyl-phenol (carvacrol/1c) exhibited much better antioxidant activity than thymol and carvacrol in DPPH assay. Ten compounds (4k, 4l, 4r, 5k, 5l, 5q, 5r, 6k, 6l and 6r) showed better or similar activity as compared to the reference compound ascorbic acid. Twenty-four most active compounds were also screened by ABTS method and showed 60-90% inhibition at 5 μg/mL concentration.
Synthesis and biological activity of 4-thiazolidinones, 2-azetidinones, 4-imidazolinone derivatives having thymol moiety
Vashi, B. S.,Mehta, D. S.,Shah, V. H.
, p. 802 - 808 (2007/10/03)
Several new 4-nitrosothymol, 4-aminothymol, 4-hydroxy-5-isopropyl-2-methylbenzalylidene aniline (2), 2-aryl-3-(4'-hydroxy-5'-isopropyl-2'-methylphenyl)-5'-H/methyl/carboxymethylthiazolidin-4-ones (3), 4-aryl-3-chloro-1-(4'-hydroxy-5'-isopropyl-2'-methylphenyl)-2-azetidinones (4), 1-(4'-hydroxy-5'-isopropyl-2'-methylphenyl)-2-methyl/phenyl-5-arylidene-4-imidazolinones (5) have been synthesised and screened for their antimicrobial and antitubercular activities.The product displayed moderate to good antimicrobial and tuberculostatic activities.The structures of theproducts 2, 3, 4, and 5 have been elucidated by elemental analyses and spectral data.
