50704-52-4

Basic information

• Product Name: Benzenepropanoic acid, 3-methoxy-, methyl ester
• CAS NO: 50704-52-4
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 50704-52-4.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, 3-methoxy-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 3-methoxy-, methyl ester(50704-52-4)
• EPA Substance Registry System: Benzenepropanoic acid, 3-methoxy-, methyl ester(50704-52-4)

Safety Data

• Hazardous Substances Data: 50704-52-4(Hazardous Substances Data)

Upstream product

• 10516-71-9 3-(3-Methoxy-phenyl)-propionic acid 
• 67-56-1 methanol 
• 626-20-0 3-methoxystyrene 
• 124-38-9 carbon dioxide 
• 579-75-9 2-Methoxybenzoic acid 
• 292638-85-8 acrylic acid methyl ester 
• 591-31-1 3-methoxy-benzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 135-02-4 ortho-anisaldehyde 
• 201230-82-2 carbon monoxide 
• 2309-07-1 Methyl ferulate 
• 74-88-4 methyl iodide 
• 6099-04-3 trans-3-methoxycinnamic acid 
• 38693-90-2 trans-3-(3-methoxyphenyl)acrylic acid methyl ester 

Downstream Products

• 119047-54-0 C₂₆H₄₀O₄Si₂ 
• 952315-95-6 dimethyl 4-(3-methoxyphenyl)-2-oxobutylphosphonate 
• 42923-77-3 6-methoxy-1,2,3,4-tetrahydro-isoquinoline 
• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 40138-66-7 3-(m-methoxyphenyl)propanal 
• 1035270-68-8 5-(3-methoxyphenyl)-3-oxo-pentanenitrile 
• 1000895-38-4 5-[2-(3-methoxyphenyl)ethyl]-1H-pyrazol-3-amine 
• 1215204-71-9 N-(2-methoxyphenyl)-2-(3-(3-methoxyphenyl)propanoyl)hydrazinecarboxamide 
• 1353757-04-6 N-(3-methoxyphenyl)-2-(3-(3-methoxyphenyl)propanoyl)hydrazinecarboxamide 
• 1353757-05-7 N-(4-methoxyphenyl)-2-(3-(3-methoxyphenyl)propanoyl)hydrazinecarboxamide 
• 1215204-70-8 3-(3-methoxyphenethyl)-4-(2-methoxyphenyl)-1H-1,2,4-triazol-5(4H)-one 
• 1353757-12-6 3-(3-methoxyphenethyl)-4-(3-methoxyphenyl)-1H-1,2,4-triazol-5(4H)-one 
• 10516-71-9 3-(3-Methoxy-phenyl)-propionic acid 
• 110339-54-3 N-[2-(3-methoxy-phenyl)-ethyl]-formamide 

Relevant articles and documents

Reduction of Electron-Deficient Alkenes Enabled by a Photoinduced Hydrogen Atom Transfer

Direct hydrogen atom transfer from a photoredox-generated Hantzsch ester radical cation to electron-deficient alkenes has enabled the development of an efficient formal hydrogenation under mild, operationally simple conditions. The HAT-driven mechanism is supported by experimental and computational studies. The reaction is applied to a variety of cinnamate derivatives and related structures, irrespective of the presence of electron-donating or electron-withdrawing substituents in the aromatic ring and with good functional group compatibility. (Figure presented.).

Palladium-Catalyzed Alkoxycarbonylation of sec-Benzylic Ethers

Herein, we report the palladium-catalyzed synthesis of 3-arylpropionate esters starting from secondary benzylic ethers. With this investigation it could be shown that ethers are suitable starting materials in addition to the established carbonylation reactions of olefins, alcohols, or aryl halides.

Meta C-H Arylation of Electron-Rich Arenes: Reversing the Conventional Site Selectivity

Controlling site selectivity of C-H activation without using a directing group remains a significant challenge. While Pd(II) catalysts modulated by a mutually repulsive pyridine-type ligand have been shown to favor the relatively electron-rich carbon centers of arenes, reversing the selectivity to favor palladation at the relatively electron-deficient positions has not been possible. Herein we report the first catalytic system that effectively performs meta C-H arylation of a variety of alkoxy aromatics including 2,3-dihydrobenzofuran and chromane with exclusive meta site selectivity, thus reversing the conventional site selectivity governed by native electronic effects. The identification of an effective ligand and modified norbornene (NBE-CO2Me), as well as taking advantage of the statistics, are essential for achieving the exclusive meta selectivity.