7252-87-1Relevant articles and documents
Annelides. 3. Complexation of Dioxygen in Organized Cobaltous Complex Assemblies. A New Approach to Kinetic Studies in Micellar Phases
Simon, J.,Moigne, J. Le,Markovitsi, D.,Dayantis, J.
, p. 7247 - 7252 (1980)
Amphiphilic ligands belonging to the Annelide class are synthesized and shown to form complexes with transition-metal cation.By aggregation, these complexes can be organized into supermolecular structures.For the first time, it is shown that the formation of micellar phases of cobaltous complexes can lead to a dramatic enhancement of the dioxygen stability constant.Kinetic measurements have been performed to elucidate the mechanism of complexation and, in particular, the respective contributions of the local concentrations, the dimensionality of the reaction, and the orientation of the reactants upon the micellar effect.A new theoretical approach is presented to rationalize the chemical reactions in micellar phases by using the Prigogine-Flory model.
NOVEL XYLENE-BASED AMPHIPHILIC COMPOUND AND USE THEREOF
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Paragraph 0178; 0179; 0208; 0216; 0221; 0246, (2018/10/19)
The present invention relates to a xylene-based amphiphilic compound, a method for preparing the same, and a method for extracting, solubilizing, stabilizing or crystallizing a membrane protein using the same. By using the xylene-based compound according to the present invention, a membrane protein may be stably stored in an aqueous solution for a long time, and may be applied in functional and structural analyses. The structural and functional analysis of the membrane protein is one of the fields of highest interest in biology and chemistry, and the xylene-based compound according to the present invention can be applied in research on protein structure that is closely related to development of a new drug.
Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation
Cho, Kyung Ho,Du, Yang,Scull, Nicola J.,Hariharan, Parameswaran,Gotfryd, Kamil,Loland, Claus J.,Guan, Lan,Byrne, Bernadette,Kobilka, Brian K.,Chae, Pil Seok
supporting information, p. 10008 - 10013 (2015/07/07)
Membrane proteins are key functional players in biological systems. These biomacromolecules contain both hydrophilic and hydrophobic regions and thus amphipathic molecules are necessary to extract membrane proteins from their native lipid environments and