725211-89-2 Usage
Uses
1-(2-Furanylmethyl)-4-piperidinemethanamine is used in the prepation of PRMT5 inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 725211-89-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,5,2,1 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 725211-89:
(8*7)+(7*2)+(6*5)+(5*2)+(4*1)+(3*1)+(2*8)+(1*9)=142
142 % 10 = 2
So 725211-89-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H18N2O/c12-8-10-3-5-13(6-4-10)9-11-2-1-7-14-11/h1-2,7,10H,3-6,8-9,12H2
725211-89-2Relevant academic research and scientific papers
PRMT5 INHIBITORS AND USES THEREOF
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Paragraph 00496, (2016/01/12)
Described herein are compounds of Formula (I)-(XIII), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.