725228-52-4

Upstream product

• 864069-20-5 4-[3-(tert-butoxycarbonylaminomethyl)phenyl]-1-[5-bromo-2-furanoyl]piperidine 
• 766-49-4 (2-fluorophenyl)acetylene 
• 725228-53-5 5-(2-fluoro-phenylethynyl)-furan-2-carbonyl chloride 
• 725228-49-9 tert-butyl 3-(piperidin-4-yl)benzylcarbamate 

Downstream Products

• 725228-46-6 [4-(3-aminomethylphenyl)piperidin-1-yl]-[5-(2-fluorophenylethynyl)furan-2-yl]-methanone trifluoroacetate 
• 725228-55-7 [4-(3-aminomethylphenyl)piperidin-1-yl]-[5-(2-fluorophenylethynyl)furan-2-yl]-methanone methanesulfonate 

Relevant academic research and scientific papers

Process for the preparation of tryptase inhibitors

This invention is directed to processes for the preparation of compounds of the formula I and their salts, which are useful as tryptase inhibitors, to intermediates useful in the preparation of such compounds, to processes for the preparation of such inte

[4-(3-AMINOMETHYLPHENYL) PIPERIDIN-1-YL]- [5-(2-FLUOROPHENYLETHYNYL)FURAN-2-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE

The present invention extends to the compund of formula (I): (I) or a prodrug, pharmaceutically acceptable salt, or solvate of said compound; to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of forumula (I), a