725247-13-2Relevant academic research and scientific papers
A lutidine-bridged bis-perimidinium salt: Synthesis and application as a precursor in palladium-catalyzed cross-coupling reactions
Tu, Tao,Malineni, Jagadeesh,Bao, Xiaoling,Doetz, Karl Heinz
, p. 1029 - 1034 (2009)
A novel lutidine-bridged bis-perimidini-um dibromide 3 was synthesized in quantitative yield from cheap commercial starting materials. The bisylidene prepared therefrom in situ upon deproto-nation is a potent precatalyst in palladium-catalyzed Heck and Suzuki cross-coupling reactions under aerobic conditions, and is efficient even with a ppm scale catalyst loading. Its stronger o-donor character is held to be responsible for its superior catalytic performance compared with imidazole- and benz-imidazole-based analogues bearing the same skeleton precursors.
