72526-76-2Relevant academic research and scientific papers
Cross metathesis approach to retinoids and other β-apocarotenoids
Wojtkielewicz, Agnieszka,Maj, Jadwiga,Dzieszkowska, Agnieszka,Morzycki, Jacek Witold
supporting information; experimental part, p. 6868 - 6875 (2011/10/02)
Cross metathesis (CM) reactions between polyenes, such as β-carotene, canthaxanthin or retinyl acetate, and various alkenes or dienes in the presence of second generation Hoveyda-Grubbs (H II) or Grubbs (G II) catalysts were investigated. Depending on the
SYNTHESYS OF THE MAJOR METABOLITES OF (2E,4E,6E,8E)- AND (2Z,4E,6E,8E)-3,7-DIMETHYL-9-(2,6,6,-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2,4,6,8-MONOTETRAENOIC ACIDS (RETINOIC ACID AND 13-cis-RETINOIC ACID)
Aig, Edward,Focella, Antonino,Parrish, David R.,Rosenberger, Michael,Scott, John W.,Zenchoff, Gladys B.
, p. 419 - 430 (2007/10/02)
Wittig condensation of (2E,4E)-triphenylphosphonium bromide with ethyl formylcrotonate or 4-hydroxy-3-methylbutenolide gives, respectively, the (all-E) and (2Z,4Z)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acids.These are converted to oxo and hydroxy metabolites of retinoic acid and 13-cis-retinoic acid.
